- IRMS - Nicolae Testemitanu SUMPh
- 1. COLECȚIA INSTITUȚIONALĂ
- MedEspera: International Medical Congress for Students and Young Doctors
- MedEspera 2020
Please use this identifier to cite or link to this item:
http://hdl.handle.net/20.500.12710/11799
Title: | Principles of migraine treatment |
Authors: | Girjev, Marina |
Keywords: | headache;chronic migraine;acute treatment;medication overuse |
Issue Date: | 2020 |
Publisher: | MedEspera |
Citation: | GIRJEV, Marina. Principles of migraine treatment. In: MedEspera: the 8th Internat. Medical Congress for Students and Young Doctors: abstract book. Chișinău: S. n., 2020, p. 280-281. |
Abstract: | Introduction. Migraine is a recurrent headache disorder affecting ∼15% of the population
during the most productive periods of their lives, between the ages of 22 and 55 years. Chronic
migraine is no longer considered a complication of migraine and is recognized in individuals that had at least five attacks fulfilling criteria for migraine with/or without aura. This disorder
affects 1,4-2,2% of the population and is associated with a higher headache impact in
comparison with the episodic migraine. Medication overuse of acute analgesics often occurs
with chronic migraine. In patients with migraine frequent intake of acute headache medication
can increase the frequency and intensity of headache, causing a vicious circle of further intake
of medication and increased attack frequency. Here is how the treatment can become the cause
of another separate condition, known as medication-overuse headache.Aim of the study. To determine medication overuse of acute treatment in patients with chronic
migraine and its impact to the severity of the disease.
Materials and methods. In this study were included 36 patients with confirmed clinical
diagnosis of chronic migraine who requested a consultation of a neurologist at the Institute of
Neurology and Neurosurgery in Chisinau. The study was based on survey: self-report
questionnaire with references to the medicamentous migraine treatment and Migraine patient
assessment questionnaire from the National Clinical Protocol. A clinical analysis of the disease
and medication intake were performed. The patients were separated in two groups: with and
without medication overuse of acute treatment (medication overuse is diagnosed if a limit
medication days per month is exceeded for ergotamines, triptans, opioids and combination
drugs ≥10 days per month, and for simple analgesics ≥15 days per month, both for longer than
3 months), based on the results of two questionnaires. Student-T test was chosen as statistical
criteria for this research.
Results. We found that patients with medication overuse of acute treatment have a significantly
more severe clinical signs of the disease. We compared the following clinical outcomes:
number of days with headache per month and intensity of headache. In case of medication
abuse we found higher values on two parameters: frequency (p<0.0001) and intensity
(p=0.0016) of headache per month.
Conclusions. On conclusion, the analysis of our data support the concept that medication
overuse is the reason for the development of more severe clinical signs in patients with existing
primary headache disorder. Patients who managed correctly their migraine attacks have
moderated clinical signs. |
URI: | https://medespera.asr.md/wp-content/uploads/ABSTRACT-BOOK.pdf http://repository.usmf.md/handle/20.500.12710/11799 |
Appears in Collections: | MedEspera 2020
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