USMF logo

Institutional Repository in Medical Sciences
of Nicolae Testemitanu State University of Medicine and Pharmacy
of the Republic of Moldova
(IRMS – Nicolae Testemitanu SUMPh)

Biblioteca Stiintifica Medicala
DSpace

University homepage  |  Library homepage

 
 
Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/12490
Title: Strategii terapeutice în chirurgia hipertensiunii portale
Other Titles: Therapeutic strategies in surgery portal hypertension
Authors: Cazacov, V.
Keywords: portal hypertension;ecoDoppler;treatment
Issue Date: 2016
Publisher: Asociaţia chirurgilor “Nicolae Anestiadi” din Republica Moldova
Citation: CAZACOV, V. Strategii terapeutice în chirurgia hipertensiunii portale = Therapeutic strategies in surgery portal hypertension. In: Arta Medica. 2016, nr. 3(60), pp. 46-47. ISSN 1810-1852.
Abstract: Introducere. Cu toate progresele recente ale metodelor de tratament, hipertensiunea portală (HTP) rămâne o problemă clinică deosebită. Scop. Analiza abordării etapizate a pacientului hepatic chirurgical asistat . Materiale si metode. Lotul de studiu constituie 346 pacienţi cirotici operați în Departamentul Chirurgie hepatobiliopancreatică. Diagnosticul include etiologia bolii, aspectul morfologic, gradul disfuncţiei hepatice, existenţa complicaţiilor, răspunsul la tratament,evoluţie şi calitatea vieţii. Rezultate. Majoritatea pacienţilor (307 pacienţi,72%) au fost diagnosticaţi cu ciroză hepatică Child B şi au asociat aspecte clinico-imagistice ale hipertensiunii portale (splenomegalie / hipersplenism, ascită, varice esofagiene). Toţi pacienţii au fost operaţi : devascularizare azygo-portală+ splenectomie(n=342), şunt portosistemic (n=3), transplant hepatic (n=1). Letalitatea postoperatorie precoce – 3,8%, morbiditatea 9,45%. Asistenţa medico-chirurgicală a pus accentul pe profilaxia posibilelor complicaţii. La 286 pacienţi cu vene esofagiene/risc hemoragic preoperator înalt şi la alţii 122 bolnavi postoperator, la distanţă, s-a efectuat ligaturarea endoscopică profilactică. Evaluarea ultrasonografică a confirmat prezenţa trombozei venei porte la 11% pacienţi splenectomizaţi : tratament antiplachetar / antitrombotic, - recanalizare. Urmărirea ecoDoppler la distanţă a confirmat că screeningul postoperator efectuat s-a dovedit eficient. Concluzii. Managementul perioperator al pacienţilor cu HTP chirurgical asistaţi este unul dificil și implică o abordare interdisciplinară şi individualizată.
Introduction. Despite recent advances in the methods of treatment of portal hypertension (HTP) remains a particular clinical problem. Purpose. Analysis of phased approach of the surgical hepatic patient. Materials. The study consists of 346 operated cirrhotic patients in the Department of Hepato-Bilio-Pancreatic Surgery. Diagnosis includes the etiology, the morphological appearance, the degree of hepatic dysfunction, the presence of complications, the treatment response, the development and quality of life. Results. The majority of patients (n = 307, 72 %) were diagnosed with liver cirrhosis Child B and associated clinical and imaging aspects of portal hypertension (splenomegaly / hypersplenism , ascites, esophageal varices). All patients were operated: azygo-portal devascularisation + splenectomy (n = 342), porto-systemic shunt (n = 3), liver transplantation (n = 1). Early postoperative lethality - 3.8%, and morbidity 9.45 %. Medical and surgical care focused on prevention of possible complications. In 286 patients with esophageal veins / high risk of preoperative bleeding and other 122 patients postoperatively, prophylactic endoscopic ligation was performed. Ultrasound examination confirmed the presence of portal vein thrombosis in 11% splenectomised patients : antiplatelet therapy / antithrombotic - recanalization. Conclusions. The perioperator management of the surgical HTP patients is a difficult. Therapeutic management implies an individualized and interdisciplinary approach.
URI: https://artamedica.md/old_issues/ArtaMedica_60.pdf
http://repository.usmf.md/handle/20.500.12710/12490
ISSN: 1810-1852
Appears in Collections:Arta Medica Vol. 60, No 3, 2016 ediție specială

Files in This Item:
File Description SizeFormat 
CAZACOV_V._Strategii.pdf170.29 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

 

Valid XHTML 1.0! DSpace Software Copyright © 2002-2013  Duraspace - Feedback