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Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/27044
Title: Features of microsurgical treatment in patients with pterygium
Authors: Fandofan, Victoria
Bozul, Uliana-Ariadna
Jeru, Ion
Keywords: recurrent pterygium;free conjunctival flap;recurrence;postoperative period;5-FU (fluoruracil)
Issue Date: 2024
Publisher: CEP Medicina
Citation: FANDOFAN, Victoria, BOZUL, Uliana-Ariadna, JERU, Ion. Features of microsurgical treatment in patients with pterygium. In: Cells and Tissues Transplantation. Actualities and Perspectives: the materials of the nat. scientific conf. with internat. particip., the 2nd ed. Chisinau, March 29-30th 2024: [abstracts]. Chişinău: CEP Medicina, 2024, p. 33. ISBN 978-9975-82-366-1.
Abstract: Bakground. Pterygium is clinically manifested by a triangular fold of the bulbar conjunctiva with the base towards the semilunar fold and the tip towards the cornea. The etiology and pathogenesis of pterygium is unknown. It would result from a corneo-conjunctival epithelial alteration, associated with a proliferation of fibrinogen tissue, progressing between the epithelium reduced to a few layers of cells and the perforated Bowman's membrane. Aim. To assess the effectiveness of a modified method in the treatment of pterygium,stage II. Objectives.1. To determine the effectiveness of the modified method using the free conjunctival flap plus subconjunctival administration of 5-FU (fluoruracil) in the treatment of patients with pterygium. 2. To appreciate the benefits of the modified method depending on the addressability of patients with pterygium. Materials and methods. The study included 8 patients (4 men and 4 women) with pterygium aged 20-71 years who underwent pterygium removal according to a modified method. Thus, during the surgical intervention, a movable, free, rectangular flap with sides 5 x 3 mm was prepared inferiorly paralimbally, which was fixed conjunctivally paralimbally, nasally in the area of the body of the pterygium translocated to the superior or inferior fornix plus subconjunctival administration of 5-FU . It is important to position the formed conjunctival flap with a limbal orientation. Discussions. The postoperative recovery was fast, but for several days after the operation the globe was hyperemic, irritating the suture fibers used to fix the conjunctival autograft. Antibiotic and anti- inflammatory in the form of eye drops are needed. Thus, in all patients, 3 months after the microsurgical intervention, no signs of recurrence of the operated pterygium were detected. In 2 late- presenting patients, the pterygium was extended onto the cornea, resulting in deep scarring. As a consequence, the radius of corneal curvature was changed with the decrease in visual acuity in the postoperative period. This is why surgery for pterygium should not have been delayed. Conclusions: 1. The microsurgical method proposed for the treatment of pterygium is safe and effective, determining the lack of recurrence in the postoperative period. 2. Microsurgical intervention based on pterygium should be performed as early as possible.
metadata.dc.relation.ispartof: Cells and tissues transplantation. Actualities and perspectives. The 2-nd edition. Chisinau, March 29-30th 2024
URI: http://repository.usmf.md/handle/20.500.12710/27044
ISBN: 978-9975-82-366-1
Appears in Collections:The Materials of the National Scientific Conference with International Participation, the 2nd edition, Chisinau, March 29-30th 2024: [Abstracts]

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