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Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/11220
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dc.contributor.authorSofian, Irina-
dc.date.accessioned2020-07-10T07:12:29Z-
dc.date.available2020-07-10T07:12:29Z-
dc.date.issued2018-
dc.identifier.citationSOFIAN, Irina. Preparation of suppositories with propolis extract. In: MedEspera: the 7th Internat. Medical Congress for Students and Young Doctors: abstract book. Chișinău: S. n., 2018, p. 262.en_US
dc.identifier.urihttps://medespera.asr.md/wp-content/uploads/Abastract-Book-2018.pdf-
dc.identifier.urihttp://repository.usmf.md/handle/20.500.12710/11220-
dc.descriptionDepartment of Drugs Technology, Nicolae Testemitanu State University of Medicine and Pharmacy of the Republic of Moldovaen_US
dc.description.abstractIntroduction. Propolis is known as one of natural products with multiple therapeutic effects, such as: antimicrobial, antibiotic, anti-inflammatory, analgesic, antioxidant, antifungal and antitumor. This apiculture product has a very complex composition, consisting of the following groups of active principles: phenols, flavonoids, amino acids, volatile oils, steroids, minerals, etc. The development of pharmaceutical forms with propolis extract is a very actual problem. Aim of the study. Technology development and standardization of suppositories with soft propolis extract. Materials and methods. Analysis of State Nomenclature of drugs of the Republic of Moldova. Use of hand rolling and molding methods and different excipients to prepare suppositories with propolis extract. Results. The analysis of State Nomenclature of drugs of the Republic of Moldova denotes a very low content of preparations with soft extract of propolis. Most of the suppositories have antiinflammatory action (25%); followed by analgesic-antipyretic (15%); immunomodulators (14%), etc. Suppositories with soft propolis extract were formulated in the compounding department of Vasile Procopisin Pharmaceutical University Center. The excipients used were cocoa butter, PEG 4000:400 (9:1) and PEG 4000:1500:400 (6:3:1). The performed quality tests on appearance, melting rate, dissolution rate and uniformity of mass met the quality standards required by European Pharmacopoeia. Conclusions. The technology of preparation of suppositories with soft propolis extract by two methods, using different excipients was elaborated and quality assessment was performed. The results of the research will allow the introduction of suppositories with soft propolis extract in assortment of Vasile Procopisin Pharmaceutical University Center as elaborations.en_US
dc.language.isoenen_US
dc.publisherMedEsperaen_US
dc.subjectpropolisen_US
dc.subjectsuppositoriesen_US
dc.subjectextracten_US
dc.titlePreparation of suppositories with propolis extracten_US
dc.typeArticleen_US
Appears in Collections:MedEspera 2018

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