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Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/12910
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dc.contributor.authorMoldovan, Irina-
dc.date.accessioned2020-11-11T17:49:20Z-
dc.date.available2020-11-11T17:49:20Z-
dc.date.issued2020-10-
dc.identifier.urihttps://stiinta.usmf.md/ro/manifestari-stiintifice/zilele-universitatii-
dc.identifier.urihttp://repository.usmf.md/handle/20.500.12710/12910-
dc.descriptionPublic Institution Nicolae Testemitanu State University of Medicine and Pharmacy of the Republic of Moldova, Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină și Farmacie „Nicolae Testemițanu” din Republica Moldova, Ziua internațională a științei pentru pace și dezvoltareen_US
dc.description.abstractIntroduction. Food allergy is an immunemediated hypersensitivity reaction that occurs as a result of exposure to a particular food allergen and occurs through cutaneous, respiratory, digestive and in other organs and systems, caused by I, III or IV types of immune reactions (Image 1). Purpose. Assessment of the spectrum of clinical manifestations in patients with Ig E-mediated food allergy (history of allergy, elimination test, specific Ig E) in correlation with the spectrum of sensitivity (clinical and laboratory methods). Material and methods. The descriptive study included 80 children aged 0-17 years with Ig E-mediated food allergy. Patients were subjected to questionnaires, which included anamnestic data, disease history, the influence of factors predisposing to the onset and progression of food allergy and complex clinical-evolutionary and laboratory examination for 1 year. Results. Sensitization of children to food changes with age: up to 7 years predominates sensitization to cow's milk, after 8 years - to cereals. According to the main clinical symptoms of food allergy, children were divided into 4 groups: with isolated skin lesions - 47%; with gastrointestinal manifestations -30%; with respiratory manifestations - 21%; with other manifestations -2%. In 1/3 of cases, polyorganic clinical manifestations were found. As the duration of the disease increases, there is a likelihood of polyorganic manifestations. A direct correlation was observed between clinical manifestations and sensitization to allergens and the predominance of immuno-pathological reactions. Conclusions. The spectrum of clinical manifestations of food allergy in children is directly correlated with the spectrum of sensitization. Both the variability of food sensitization and the spectrum of clinical manifestations can change as the child grows.en_US
dc.language.isoenen_US
dc.publisherUniversitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu"en_US
dc.subjectfood allergyen_US
dc.subjectpediatricsen_US
dc.subjectdescriptive studyen_US
dc.titleThe spectrum of clinical manifestations of food allergy in childrenen_US
dc.typeOtheren_US
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