USMF logo

Institutional Repository in Medical Sciences
of Nicolae Testemitanu State University of Medicine and Pharmacy
of the Republic of Moldova
(IRMS – Nicolae Testemitanu SUMPh)

Biblioteca Stiintifica Medicala
DSpace

University homepage  |  Library homepage

 
 
Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/13048
Full metadata record
DC FieldValueLanguage
dc.contributor.authorLazăr, Cornelia
dc.contributor.authorVozian, Marin
dc.contributor.authorPantea, Valeriana
dc.contributor.authorMișina, Ana
dc.contributor.authorTagadiuc, Olga
dc.date.accessioned2020-11-18T11:58:27Z
dc.date.available2020-11-18T11:58:27Z
dc.date.issued2019
dc.identifier.citationLazăr, Cornelia, Vozian, Marin, Pantea, Valeriana, [et al]. Ischemia modified albumin in experimental ovarian torsion with and without controlled reperfusion. In: Revista Română de Medicină de Laborator. 2019, vol. 27, nr. 1, pp. 43-50. DOI:10.2478/rrlm-2019-0008en_US
dc.identifier.issn2284-5623
dc.identifier.issnL 1841-6624
dc.identifier.otherDOI: https://doi.org/10.2478/rrlm-2019-0008
dc.identifier.urihttp://www.rrml.ro/articole/articol.php?year=2019&vol=1&poz=5
dc.identifier.urihttp://repository.usmf.md/handle/20.500.12710/13048
dc.descriptionBiochemistry and Clinical Biochemistry Department, Nicolae Testemitanu State University of Medicine and Pharmacy, Chişinău; Surgery nr.1 “Nicolae Anestiadi” Department, Nicolae Testemitanu State University of Medicine and Pharmacy, Chişinău; Laboratory of Biochemistry, Nicolae Testemitanu State University of Medicine and Pharmacy, Chişinău; Department of Surgical Gynecology, Mother and Child Institute, Chişinău.en_US
dc.description.abstractPurpose: Ovarian torsion, being a gynecological emergency, requires to be rapidly diagnosed and treated with minimal consequences on ovarian function after the removal of torsion. As ischemia modified albumin (IMA) is considered a good biomarker in diverse ischemic diseases, the aim of our study was to determine the effect of different ovarian torsion/detorsion models on serum and ovarian homogenates levels of IMA in an experimental study. Methods: IMA was measured in the serum and ovarian homogenates of 7 groups of female rats (10 animals in each group): 1 - control (no intervention); 2 - sham (only laparotomy); 3 - ischemia group: 3 hours ovarian torsion (OT); 4 - 3 hours OT (ischemia), 1 hour simple reperfusion; 5 - 3 hours ischemia, 1 hour controlled reperfusion that was assured during the first two minutes by opening and closing the clips on the ovarian pedicles in 10 seconds intervals, followed by simple reperfusion; 6 - 3 hours ischemia, 24 hours simple reperfusion; 7 - 3 hours OT, 24 hours controlled reperfusion. The results were analyzed by Welch’s ANOVA and Spearman correlation. Results: Ischemia increases the IMA in both serum and ovarian homogenates compared to control and sham groups. The controlled reperfusion groups had a statistically significant lower IMA in serum compared to simple reperfusion groups. IMA was found to be higher in the ovarian homogenates of simple reperfusion compared to controlled reperfusion groups. Conclusion: Our results suggest that controlled reperfusion prevent the processes that increase the IMA in ovarian torsion.en_US
dc.language.isoenen_US
dc.publisherRevistei Române de Medicină de Laborator - Romanian Journal of Laboratory Medicineen_US
dc.subjectovarian torsionen_US
dc.subjectischemia modified albuminen_US
dc.titleIschemia modified albumin in experimental ovarian torsion with and without controlled reperfusionen_US
dc.typeArticleen_US
Appears in Collections:ARTICOLE ȘTIINȚIFICE



Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

 

Valid XHTML 1.0! DSpace Software Copyright © 2002-2013  Duraspace - Feedback