USMF logo

Institutional Repository in Medical Sciences
of Nicolae Testemitanu State University of Medicine and Pharmacy
of the Republic of Moldova
(IRMS – Nicolae Testemitanu SUMPh)

Biblioteca Stiintifica Medicala
DSpace

University homepage  |  Library homepage

 
 
Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/13263
Full metadata record
DC FieldValueLanguage
dc.contributor.authorGroppa, Liliana-
dc.contributor.authorSârbu, Oxana-
dc.date.accessioned2020-11-25T11:13:20Z-
dc.date.available2020-11-25T11:13:20Z-
dc.date.issued2020-10-
dc.identifier.urihttps://stiinta.usmf.md/ro/manifestari-stiintifice/zilele-universitatii-
dc.identifier.urihttp://repository.usmf.md/handle/20.500.12710/13263-
dc.descriptionDepartment of Internal Medicine,"Nicolae Testemitanu" State University of Medicine and Pharmacy, Republic of Moldova, Chisinau, Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină și Farmacie „Nicolae Testemițanu” din Republica Moldova, Ziua internațională a științei pentru pace și dezvoltareen_US
dc.description.abstractIntroduction: In ankylosing spondylitis, it is difficult to start treatment early because of delayed diagnosis in men about 8.4 years, and in women 9.8 years from the onset of the disease. This is related to a number of subjective and objective factors. Purpose: early diagnosis in ankylosing spondylitis in women. Material and methods: In order to perform the study and satisfy the proposed objectives, 40 patients with the diagnosis established by AS, aged between 18-60 years, disease duration 7.2 ± 0.3 years were investigated. It was assessed for joint pain syndrome by analog visual scale, evaluation of inflammation indices: Creactive protein, fibrinogen, ESR, HLA-B27, sacroiliac joint radiograph and HAQ index. Results: When analyzing the visual analog scale of the disease, the joint pain syndrome is much stronger in women with HLA B27 positive. Among the laboratory indices of inflammation, the mean value of ESR in the HLA B27-positive group was 28 mm / h compared with 17 in those with HLA B27 negative, the C-reactive protein values in the HLA B27-positive group were 43 mg / dl with HLA B 27 negative 21 mg / dl. The BASFI index had a prevalence in the group of patients with HLA B27 positive. HLA-B27 was present in 36 (90%) cases. In all evaluated patients sacroiliitis was present in 100% of cases, of which st Rg II in patients with HLA B27 negative compared to St Rg II in those with HLA B27 positive. The HAQ index was on average 15-40 in women with HLA B27 positive, compared with 12-30 in those with HLA B27 negative. Conclusions: For women with HLA B27 positive at the onset of the disease, it is characterized by a faster progression of sacroiliac joint damage, and a much more pronounced pain syndrome and a lower functional capacity compared to patients with HLA B27 negative. Highlighting the presence of HLA B-27 antigen in the blood at the early stages of the disease would allow the diagnosis of ankylosing spondylitis to be established, early initiation of background treatment and stopping the progression of the process.en_US
dc.language.isoenen_US
dc.publisherUniversitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu"en_US
dc.subjectankylosing spondylitisen_US
dc.subjectsacroiliac jointsen_US
dc.subjectHLA-B27en_US
dc.titleEarly diagnosis in ankylosing spondylitis in womenen_US
dc.typeOtheren_US
Appears in Collections:Culegere de postere

Files in This Item:
File Description SizeFormat 
Groppa_Sarbu_EARLY_DIAGNOSIS_IN_ANKYLOSING_SPONDYLITIS_IN_WOMEN_p.168.pdf569.7 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

 

Valid XHTML 1.0! DSpace Software Copyright © 2002-2013  Duraspace - Feedback