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Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/14866
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dc.contributor.authorCurchi, Mirela-
dc.contributor.authorDeseatnicova, Elena-
dc.contributor.authorAgachi, Svetlana-
dc.contributor.authorRotaru, Larisa-
dc.contributor.authorGroppa, Liliana-
dc.date.accessioned2021-01-08T07:45:17Z-
dc.date.available2021-01-08T07:45:17Z-
dc.date.issued2020-
dc.identifier.citationCURCHI, Mirela, DESEATNICOVA, Elena, AGACHI, Svetlana, et al. Clinical features in patients with systemic lupus erythematosus = Particularitățile clinice la pacienții cu lupus eritematos systemic. In: Congresul consacrat aniversării a 75-a de la fondarea USMF „Nicolae Testemițanu”, 21-23 octombrie 2020: Abstract book. Chișinău: [s. n.], 2020, p. 212.en_US
dc.identifier.urihttps://stiinta.usmf.md/sites/default/files/inline-files/Abstract%20Book.%20CULEGERE%20DE%20REZUMATE%20.pdf-
dc.identifier.urihttp://repository.usmf.md/handle/20.500.12710/14866-
dc.description.abstractBackground. Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that can affect any organ or system. It develops on the background of genetically imperfect immunity, associated with hyperproduction of anti-nuclear antibodies. It is characterized by a variety of clinical picture. Objective of the study. To determine specific clinical features in patients with systemic lupus erythematosus. Material and Methods. 64 patients with systemic lupus erythematosus arthritis admitted consecutively in the Rheumatology department of CRH Timofei Moșneaga in 2019 were examined. To determine the clinical features of the patients, a questionnaire was completed according to the diagnostic criteria, risc factors et.al. The data obtained were statistically analyzed. Results. 52 (81.4%) of the examinated patients were women and 12 (18.6%) were men. The mean age of the examined persons was 48.3 ± 8.7 years, the duration of the disease was in average of 12.15 ± 9.32 years. In the examined group 98% had musculoskeletal manifestations and at the same time 85% showed mucocutaneous manifestations. The most common was alopecia at 89.06%, and malar rush at 60.9% of patients. Cardiovascular pathology was found in 35.7%, and pulmonar at 63,8%. At the analysis of patients with SLE 30.3% of them had renal involvement manifested by proteinuria in 47.8% and hematuria in 31.3%. CNS pathology was manifested by 78,5% headache and polyneuropthy in 24,6%. Conclusion. Musculoskeletal manifestations are the most common in SLE. It is necessary to conduct investigations of the respiratory, cardiovascular, renal and nervous systems in SLE at the early stages for timely determination of the pathology and treatment. Introducere. Lupusul eritematos sistemic (LES) este o boală autoimună cronică, care afectează orice organ sau sistem. Se dezvoltă pe fondul imunității imperfecte determinate genetic cu hiperproducerea anticorpilor anti-nucleari. Tabloul clinic poate fi variat. Scopul lucrării. De a determina particularitățile tabloului clinic la pacienții cu lupus eritematos sistemic. Material și Metode. Au fost examinați 64 de pacienți cu lupus eritematos sistemic, internați consecutiv în secția reumatologie a SCR Timofei Moșneaga în 2019. Pentru determintarea particularităților clinice a pacienților a fost completat un chestionar conform criteriilor de diagnosticare, factorilor de risc etc. Datele obținute au fost analizate statistic. Rezultate. Dintre pacienții examinați 52 (81,4%) femei și 12 (18,6%) bărbați. Vârsta medie a constituit 48,3±8,7 ani, iar durata maladiei cu o medie de 12,15±9,32 ani. Din grupul examinat 98% au avut mafestări musculoscheletale la debut și concomitent 85% mafestări mucocutanate. Din ele mai frecvente au fost alopecie 89,06 %, rush malar 60,9 %. Manifestările pulmonare au fost diagnosticate la 63,8% din pacienți, cardiovasculare la 35,7%. La analiza pacienților cu lupus eritematos de sistem 30,3% dintre ei au avut manifestări renale prin prezența proteinuriei în 47,8 % și hematuriei la 31,3% din pacienții examinați. Afectarea SNC s-a manifestat prin cefalee 78,5% și polineuropatie la 24,6%. Concluzii. Manifestările musculoscheletale sunt mai frecvente la pacienții cu lupus LES. Este necesar de a efectua investigații ale aparatului respirator, cardiovascular, renal și nervos în LES, chiar la debut pentru determinarea precoce a patologiei, complicației acesteia și aplicarea tratamentului.en_US
dc.publisherUniversitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldovaen_US
dc.subjectsystemic lupus erythmatosisen_US
dc.subjectclinical featuresen_US
dc.titleClinical features in patients with systemic lupus erythematosusen_US
dc.title.alternativeParticularitățile clinice la pacienții cu lupus eritematos sistemicen_US
dc.typeOtheren_US
Appears in Collections:Congresul consacrat aniversării a 75-a de la fondarea USMF „Nicolae Testemițanu”, 21-23 octombrie 2020: Abstract book

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