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Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/17333
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dc.contributor.authorHovanscaia, Diana-
dc.contributor.authorSerbenco, A.-
dc.contributor.authorStoianov, Natalia-
dc.contributor.authorGroppa, St.-
dc.date.accessioned2021-06-04T08:50:01Z-
dc.date.available2021-06-04T08:50:01Z-
dc.date.issued2018-
dc.identifier.citationHOVANSCAIA, Diana, SERBENCO, A., STOIANOV, Natalia, GROPPA, St. Particularităţile clinico-evolutive ale epilepsiei în sarcină şi naştere. In: Buletin de perinatologie. 2018, nr. 3(79), pp. 62-66. ISSN 1810-5289.en_US
dc.identifier.issn1810-5289-
dc.identifier.urihttps://mama-copilul.md/images/buletin-perinatologic/BP_2018/3_2018(9).pdf-
dc.identifier.urihttp://repository.usmf.md/handle/20.500.12710/17333-
dc.descriptionUniversitatea de Stat de Medicină şi Farmacie “ Nicolae Testemiţanu”en_US
dc.description.abstractIntroduction. To describe the epilepsy evolution, the anamnestic particularities, the beginning, the type and frequency of epileptic seizures, and antiepileptic treatment, there were studied pregnancy and delivery in women with epilepsy. Materials and methods: The transversal retrospective study included an analysis of 153 deliveries in women with epilepsy that took place in the Institute of Mother and Child Care, Chisinau, Republic of Moldova, during 2010-2014. Results: During the study, it was found out that the beginning of epilepsy prevails in puberty, in 88 cases (57,5 ± 4,0%). In 2 cases (1,3 ± 0,9%) it was observed primary appearance of epilepsy in pregnancy, which shows us gestational epilepsy. In the patients under study, it was observed the predominance of the structural- metabolic (symptomatic) form of the disease – 103 cases (67,3 ± 3,8%). This study showed that in women with frequent seizures of epilepsy before the pregnancy – 43 (22,1 ± 3,4%), the frequency of seizures during pregnancy did not change – 41 (26,8 ± 3,6% ). During pregnancy 69 (45,1 ± 4,0%) patients did not take antiepileptic treatment, 15 ( 9,8% ± 2,4) canceled the treatment on their own, and in 23 (15 ± 2,9%) patients the antiepileptic therapy was primarily prescribed during pregnancy, due to the primary appearance or increasing frequency of epileptic seizures. And only 61 (39,9 ± 4,0%) women strictly followed the epileptologist’s recommendations. In 3 (2,0 ± 1,3%) cases the birth process was complicated by the emergence of tonic-clonic seizures, and in 8 (5,2 ± 1,8%) cases epileptic seizures were noted in the early postpartum period. Conclusions: Analysis of own data indicates that increased frequency of the epileptic seizures was observed in pregnant women which did not take any antiepileptic treatment or who canceled the treatment on their own. The postpartum period is vulnerable in women with epilepsy due to disturbed nighttime sleep, the presence of dolor syndrome and psycho-emotional stress, as well as the changes in the pharmacokinetics of antiepileptic drugs and low compliance of mother to the dosing regimen.en_US
dc.description.abstractБыли изучены особенности анамнеза, возраст дебюта, длительность течения и характер эпилепсии, форма и применяемое противоэпилептическое лечение у женщин, страдающих эпилепсией во время беременности, родов и в послеродовом периоде. Материалы и методы: Был проведен трансверсальный ретроспективный анализ 153 родов у женщин с эпилепсией, родивших в Институте Матери и Ребенка в г. Кишиневе, Республика Молдова, в течение 2010-2014 гг. Результаты: В ходе исследования выявлено преобладание дебюта эпилепсии в пубертатном возрасте 88 случаев (57,5± 4,0%). В 2 случаях (1,3 ± 0,9%) отмечено первичное появление эпилептических приступов во время беременности, т.е. идет речь о гестационной эпилепсии. У исследуемых пациенток отмечено преобладание структурально-метаболической (симптоматической) формы заболевания -103 случая (67,3 ± 3,8%). Настоящее исследование показало, что у пациенток с частыми приступами до беременности 43(22,1 ± 3.4%) частота приступов во время беременности не изменилась -41 ( 26,8 ± 3,6% ). Во время беременности 69 (45,1 ± 4,0%) пациенток не принимали противоэпилептического лечения, 15 ( 9,8% ± 2,4) отменили самостоятельно себе терапию, a 23-м (15 ± 2,9%) терапия первично назначена во время беременности, вследствие первичного появления или учащения приступов. И лишь 61 женщина (39,9 ± 4,0%) строго придерживалась рекомендациям эпилептолога. В 3 случаях (2,0 ± 1,3%) процесс родов осложнился появлением тонико-клонических судорог, а в 8-ми (5,2 ± 1,8%) эпилептические припадки отмечались в раннем послеродовом периоде.en_US
dc.language.isoroen_US
dc.publisherInstituţia Medico-Sanitară Publică Institutul Mamei și Copiluluien_US
dc.relation.ispartofBuletin de perinatologieen_US
dc.subjectepilepsyen_US
dc.subjectpregnancy and childbirthen_US
dc.subjectantiepileptic therapyen_US
dc.subjectepileptic seizureen_US
dc.titleParticularităţile clinico-evolutive ale epilepsiei în sarcină şi naştereen_US
dc.title.alternativeClinical evolution particularities of epilepsy in pregnancy and deliveryen_US
dc.title.alternativeКлинико-эволютивные особенности эпилепсии во время беременности и родовen_US
dc.typeArticleen_US
Appears in Collections:Buletin de Perinatologie Nr. 3(79) 2018

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