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Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/17680
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dc.contributor.authorЗыков, А.С.
dc.contributor.authorБачман, Е.Н.
dc.contributor.authorМогилевкина, И.А.
dc.date.accessioned2021-06-11T08:16:06Z
dc.date.available2021-06-11T08:16:06Z
dc.date.issued2014
dc.identifier.citationЗЫКОВ, А.С., БАЧМАН, Е.Н., МОГИЛЕВКИНА, И.А. Диагностика преждевременного разрыва плодных оболочек. В: Buletin de perinatologie. 2014, № 1(61), сс. 15-19. ISSN 1810-5289.en_US
dc.identifier.issn1810-5289
dc.identifier.urihttps://www.mama-copilul.md/images/buletin-perinatologic/BP_2014/1_2014.pdf
dc.identifier.urihttp://repository.usmf.md/handle/20.500.12710/17680
dc.descriptionКафедра акушерства, гинекологии и перинатологии ФИПО, Донецкий национальный медицинский университет им. М. Горького, Донецк, Украина, Областной перинатальный центр, Хмельницкий, Украинаen_US
dc.description.abstractObjectіve. Calculation of predictive value, sensitivity and specificity of the diagnostic test ActimPROM for premature rupture of membranes detection. Material and methods. In prospective study 27 pregnant women between 24 and 41 gestational weeks who have been admitted to the Donetsk Regional Center for Maternal and Child Protection during June 1- August 1, 2011 with suspected premature rupture of the membranes (PROM) without uterine contractions were included. “Fern” test and ActimPROM have been used. The tests diagnostic capabilities were calculated in comparison to final clinical diagnosis of PROM. Both tests prognostic values were compared. Sensitivity, specificity and predictive value of the tests were evaluated by statistical package MedStat (Lyakh J.E., Gurianov V.G., 2004- 2012) using logistic regression and constructing ROC - curve. p<0,05 was considered statistically significant. Results. On admission there was: in 21 cases suspected and in 6 – obvious leakage of water due to premature rupture of the membranes. Test ActimPROM has demonstrated sensitivity of 100% (95% CI, 82.4% -100%), specificity - 83.,3% (95% CI 35,9% -99,6%), the likelihood ratio + LR = 6,0 (95% CI 1,0-35,9). The “fern” test sensitivity was 73,7% (95% CI 48,8% -90,9%), specificity - 33,3% (95% CI 4,3% -77,7%), the likelihood ratio + LR = 1,1 (95% CI 0,6-2,1). -LR = 0,8 (95% CI 0,2-3,1). According to logistic regression analysis, the “fern” test is unsuitable for PROM detection. Conclusions. Use of ActimPROM test increases precision of premature rupture of the membranes diagnosis. Simplicity and speed in getting the test results let us to recommend its use in obstetric practice. We do not recommend use of the “fern” test in view of its low diagnostic properties.en_US
dc.description.abstractObiectuvul. Calcularea valorii predictive, sensibilităţii şi specificităţii testului ActimPROM pentru diagnosticarea rupturii premature a membranelor (RPM). Materiale şi metode. Studiul prospectiv a inclus 27 de femei gravide între 24 şi 41 de săpt. de sarcina, care au fost admise la Centrul Regional din Donetsk pentru Ocrotirea Mamei şi Copilului în perioada 1 iunie - 1 august, 2011, cu suspecţie la ruptura prematură a membranelor fără contracţii uterine. Testele "Fern" şi ActimPROM au fost utilizate. Capacităţile de diagnostic ale testelor s-au calculat în comparaţie cu diagnosticul clinic final de RPM. Valorile prognostice ale ambelor teste au fost comparate. Sensibilitate, specificitate şi valoarea predictivă a testelor au fost evaluate prin pachetul statistic MedStat (Lyakh JE, Gurianov VG, 2004-2012) folosind regresia logistică şi construirea curbii ROC. p<0,05 a fost considerat statistic semnificativ. Resultate. La internare s-au înregistrat: 21 de cazuri de suspecţie şi 6 cazuri de scurgere evidentă a lichidului ca urmare a rupturii premature a membranelor. Testul ActimPROM a demonstrat sensibilitate de 100% (95% CI, 82.4%-100%), specificitate – 83.3% (95% CI 35,9%-99,6%), raportul probabilităţii + LR = 6,0 (CI 95%, 1,0-35,9). Sensibilitatea testului "fern" a fost de 73,7% (95% CI 48,8%-90,9%), specificitate - 33,3% (95% CI 4,3%-77,7%), raportul probabilităţii + LR = 1,1 (95% CI 0,6-2,1). -LR = 0,8 (95% CI 0,2-3,1). Conform analizei de regresie logistică, testul "fern" nu este potrivit pentru detectarea RPM. Concluzii. Utilizarea testului ActimPROM creşte precizia diagnosticului de RPM. Simplicitatea şi viteza în obţinerea rezultatelor testului ne permite a-l recomanda pentru utilizare în practică obstetricală. Noi nu recomandăm utilizarea testului "fern", având în vedere proprietăţile sale reduse de diagnostic.ro
dc.language.isoruen_US
dc.publisherInstituţia Medico-Sanitară Publică Institutul Mamei și Copiluluien_US
dc.relation.ispartofBuletin de perinatologieen_US
dc.subjectpregnancyen_US
dc.subjectpremature rupture of the membranesen_US
dc.subjectsensitivity and specificityen_US
dc.subject“fern” testen_US
dc.subjectprotein-1en_US
dc.subjectinsulin-like growth factor bindingen_US
dc.titleДиагностика преждевременного разрыва плодных оболочекru
dc.title.alternativePremature rupture of the membranes diagnosisen_US
dc.title.alternativeDiagnosticul rupturii premature a membranelorro
dc.typeArticleen_US
Appears in Collections:Buletin de Perinatologie Nr. 1(61) 2014

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