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Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/18073
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dc.contributor.authorRotaru, Lilia
dc.date.accessioned2021-10-02T19:54:06Z
dc.date.available2021-10-02T19:54:06Z
dc.date.issued2021
dc.identifier.citationROTARU, Lilia. Results of the cohort study of cognitive impairment associated with Parkinson's disease. In: The Moldovan Medical Journal. 2021, vol. 64, no 3 (Neuro Congress Issue), p. 29. ISSN 2537-6381.
dc.identifier.issn2537-6381
dc.identifier.issn2537-6373
dc.identifier.urihttp://moldmedjournal.md/wp-content/uploads/2021/09/Congres-Neuro-2021-Spaltul-11.pdf
dc.identifier.urihttp://repository.usmf.md/handle/20.500.12710/18073
dc.description.abstractBackground: Cognitive impairment (CI) is frequent in Parkinson’s Disease (PD), having particular features. Material and methods: Sixty-five consecutive PD patients, (mean age 64.87 ± 7.69 y.o.; disease duration 50.21 ± 38.61 mo.; 48 women (43.2%), 63 men (56.8%)) underwent MoCA and Beck tests. Cognitive status was graded as: (1) normal and (2) impaired cognition. Results: There were similar: ages (65.79 ± 7.13 vs 62.17 ± 12.21 y.o.), onset ages (61.44 ± 7.61 vs 57.00 ± 12.95 years), disease duration (49.63 ± 36.78 vs 66.00 ± 26.48) months, levodopa (574.58 ± 129 vs 249.55) and agonists doses (5.19 ± 3.02 vs 1.05 ± 0.05) and Beck scores (8.13 ± 6.21 vs 7.4 ± 3.85), in groups. CI was present in 59 (90.8%) patients; more frequent patients with cardiovascular risk factors (91.7% vs 80.0%, p > 0.05), symmetrical parkinsonism (41 pts (93.2%) vs 18 pts (85.7%), p > 0.05), and in first disease symptom bradykinesia patients (30 pts (93.8%) vs 23 pts (85.2%), p > 0.05). Upper / Lower Asymmetry Indexes (0.60 ± 0.37 vs 2.4 ± 0.97, p > 0.05) were lower in CI patients, all lower type patients (15 pts (100%) vs 18 pts (85.6%), p > 0.05) having CI. MoCA scores correlated with UPDRS on (r = -0.320, p <0.022), and red flags number (r = -0.590, p < 0.006). Conclusions: CI is more expectable in akinetic, symmetric and lower type parkinsonism, also in patients with cardiovascular risk factors, with probable PD, and a more motor impairment.en_US
dc.language.isoenen_US
dc.publisherThe Scientific Medical Association of the Republic of Moldovaen_US
dc.relation.ispartofThe Moldovan Medical Journalen_US
dc.subjectcognitive impairmenten_US
dc.subjectParkinson diseaseen_US
dc.subjectcohort studyen_US
dc.titleResults of the cohort study of cognitive impairment associated with Parkinson's diseaseen_US
dc.typeOtheren_US
Appears in Collections:The Moldovan Medical Journal, Vol. 64, No 3, September 2021

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