USMF logo

Institutional Repository in Medical Sciences
of Nicolae Testemitanu State University of Medicine and Pharmacy
of the Republic of Moldova
(IRMS – Nicolae Testemitanu SUMPh)

Biblioteca Stiintifica Medicala
DSpace

University homepage  |  Library homepage

 
 
Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/19860
Full metadata record
DC FieldValueLanguage
dc.contributor.authorBanov, Pavel
dc.date.accessioned2022-02-01T08:47:05Z
dc.date.available2022-02-01T08:47:05Z
dc.date.issued2012
dc.identifier.citationBANOV, P. Efficacy of Proflosin' in conservative management of ureteral stones. In: MedEspera: the 4th Internat. Medical Congress for Students and Young Doctors: abstract book. Chișinău: S. n., 2012, pp. 141-142.en_US
dc.identifier.urihttp://repository.usmf.md/handle/20.500.12710/19860
dc.description.abstractIntroduction: Medical expulsion therapy is a first - line for treatment of small ureteral calculi. Tamsulosin is the studied drug, but data received regarding its effectiveness are controversial and its administration is discussible. We aimed to assess the effect of tamsulosin as adjuvant therapy for ureteral calculi. Material and Methods: There were 64 patients examined with primary and recurrent ureterolithiasis. The presence of ureterolithiasis was assessed by ultrasound and/or radiological examination of upper urinary tract. Patients were analyzed for age, gender, stone size (>7 mm excluded) and location (side, upper, medium and lower 1/3 of ureter, kidney stones excluded), presence of UTI, chronic concomitant diseases. The patients were randomly divided into two groups - Group 1 -4 4 patients underwent the standard therapy with addition of Proflosin (Tamsulosin 0,4 mg) Berlin-Chemie/Menarini once a day, and 20 patients (Group II) - standard therapy only. Patients were offered a closely monitored trial for spontaneous stone passage in 4-week period prior to definitive therapy. The stone expulsion rate, VAS score and number of colic attacks, time of stone elimination and possible side effects of medication were observed. Results: All patients completed the study and none was excluded due to side effects. No significant differences were found between the groups for age, gender, stone size and location. Mean patient age was 45±6,8 years. There were 26 females and 38 males. The stone-free rate was 88,6% in Group I (39/44), compared with 70,0% (14/20) in Group II. Mean of colic attacks was 2,6±0,3 in Group I compared with 7,2±0,8 in Group II (p>0,001), and VAS score was 4 and 7 in Group I and II respectively. A mean stone expulsion time of 8,2 and 14,5 days was recorded for Group I and II respectively, and this difference was statistically significant (p<0,001). Conclusions: The adjunction of tamsulosin for conservative management of ureteral calculi decrease the time of stone expulsion, number of colic attacks and amount of analgesics. The Proflosin demonstrated no clinically significant adverse effects, while proving to be a safe and effective treatment option.en_US
dc.language.isoenen_US
dc.publisherState Medical and Pharmaceutical University Nicolae Testemitanu, Medical Students and Residents Association, Scientific Association of Students and Young Doctorsen_US
dc.relation.ispartofMedEspera: The 4th International Medical Congress for Students and Young Doctors, May 17-19, 2012, Chisinau, Republic of Moldovaen_US
dc.subjecttamsulosinen_US
dc.subjectureteral stonesen_US
dc.subjectexpulsion therapyen_US
dc.subjectProflosinen_US
dc.titleEfficacy of Proflosin' in conservative management of ureteral stonesen_US
dc.typeOtheren_US
Appears in Collections:MedEspera 2012

Files in This Item:
File Description SizeFormat 
EFFICACY_OF_PROFLOSIN_IN_CONSERVATIVE_MANAGEMENT_OF_URETERAL_STONES.pdf1.41 MBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

 

Valid XHTML 1.0! DSpace Software Copyright © 2002-2013  Duraspace - Feedback