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Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/20162
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dc.contributor.authorSidorenko, Svetlana-
dc.contributor.authorSidorenko, Ludmila-
dc.contributor.authorCheplyaka, Alexey-
dc.date.accessioned2022-02-16T08:04:32Z-
dc.date.available2022-02-16T08:04:32Z-
dc.date.issued2010-
dc.identifier.citationSIDORENKO, Svetlana, SIDORENKO, Ludmila, CHEPLYAKA, Alexey. Study of ultrastructure in mitochondria of acinar cells in demarcation line in experimental pancreatic necrosis. In: MedEspera: the 3rd Internat. Medical Congress for Students and Young Doctors: abstract book. Chișinău: S. n., 2010, pp. 19-20.en_US
dc.identifier.urihttp://repository.usmf.md/handle/20.500.12710/20162-
dc.description.abstractThe objective of the study was to analyze the ultrastructure in mitochondria of acinar cells in demarcation line in experimental pancreatic necrosis. Investigations were done on 3 dogs. Pancreatic necrosis was formed by injection of 1% potassium permanganate solution in pancreatic parenchyma. Materials for electronic microscopy were taken from animals 3 hours after potassium permanganate injection. In comparison to the mitochondria of pancreacyte in peripheric area, in demarcation line these organelles had a round, global form, whereas extended mitochondria weren't found. Instead of a correct mutually parallel arrangement, most of the crists were reduced, in disorder, or even absent. Mitochondrial matrix was light as used for globe extension. The volume of mitochondria increased in demarcation line, but the common length of internal membranes was double reduced. The length of internal mitochondrial membranes mostly adequate reflects the respiratory status and synthesis of ATP in pancreacytes. Mitochondria of acinar cells in demarcation line are characteristic for organelles with dismatched oxidation and phosphorilation which conductes to reduced energy generation and consequently to pancreatic necrosis. By damaging the mitochondrial membrane cytochrome C get lost, that is one of the components of respiratory circle and important element in energy production. To involve in treatment program actions for energetic stabilization in perspective are planed investigations of cytochrome C influence on ultrastructure in mitochondria of acinar cells in demarcation line in experimental pancreatic necrosis.en_US
dc.language.isoenen_US
dc.publisherNicolae Testemitanu State Medical and Pharmaceutical Universityen_US
dc.relation.ispartofMedEspera: The 3rd International Medical Congress for Students and Young Doctors, May 19-21, 2010, Chisinau, Republic of Moldovaen_US
dc.titleStudy of ultrastructure in mitochondria of acinar cells in demarcation line in experimental pancreatic necrosisen_US
dc.typeOtheren_US
Appears in Collections:MedEspera 2010



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