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Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/2044
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dc.contributor.authorGladîş, Valentina
dc.contributor.authorCorcimaru, Ion
dc.contributor.authorRobu, Maria
dc.contributor.authorChelea, Iurie
dc.contributor.authorOleinicov, Elena
dc.contributor.authorPlaschevici, Irina
dc.contributor.authorŞaraev, Svetlana
dc.date.accessioned2019-06-22T14:26:36Z-
dc.date.available2019-06-22T14:26:36Z-
dc.date.issued2013
dc.identifier.citationGLADÎŞ, Valentina, CORCIMARU, Ion. et al. Eficacitatea tratamentului leucemiei acute promielocitare la copii şi adulţi. In: Anale Științifice ale IP USMF “Nicolae Testemiţanu”. Ed. a 14-a. Chișinău: CEP Medicina, 2013, Vol. 3: Probleme actuale în medicina internă, pp460-464en_US
dc.identifier.urihttp://repository.usmf.md/handle/20.500.12710/2044-
dc.descriptionCatedra Hematologie, oncologie şi terapie de campanie USMF “Nicolae Testemiţanu”, IMSP Institutul Oncologic din Republica Moldovaen_US
dc.description.abstractEfficacy was studied in 91 patients with acute promyelocytic leukemia (APL) in five age groups: 5-12 years, 13-18 years, 19-40 years, 41-60 years and above 60 years. The treatment with all-trans retinoid acid (ATRA) in combination with cycles polichimioterapie „5+2”, „7+3” was performed in all patients . It was found that LAP has developed more frequently in people aged 19-40. Efficacy of the treatment was higher in age groups 13-18 years, 19-40 years and over 60 years (80%, 85%, 85,7% respectively). Relapses occurred more frequently in children aged 5-12 years (75%) and patients aged over 60 years (66,7%). Age of patients with APL 5-12 years may be considered as an unfavorable prognostic factor. A fost studiată eficacitatea tratamentului la 91 pacienţi cu leucemia acută promielocitară (LAP) în 5 grupuri de vîrstă: 5-12 ani, 13-18 ani, 19-40 ani, 41-60 ani şi de peste 60 ani. La toţi bolnavii s-a efectuat tratament cu acidul all-trans-retinoid (ATRA) în combinatie cu cicluri de polichimiotepaie „5+2”, „7+3”. A fost constatat ca LAP s-a dezvoltat mai frecvent la persoanele cu vîrsta 19-40 ani. Eficacitatea tratamentului a fost mai înaltă în grupurile de vîrstă 13-18 ani, 19-40 ani şi peste 60 ani ( 80%, 85%, 85,7% respectiv).Recidivele LAP au avut loc mai frecvent la copiii cu vîrsta 5-12 ani (75%) şi pacienţii cu vîrsta de peste 60 ani (66,7%).Vărsta pacienţilor cu LAP de 5-12 ani poate fi considerată ca un factor de prognostic nefavorabil.en_US
dc.language.isootheren_US
dc.publisherCEP "Medicina"en_US
dc.subject.meshLeukemia, Promyelocytic, Acuteen_US
dc.subject.meshChilden_US
dc.subject.meshAdulten_US
dc.subject.meshRetinoidsen_US
dc.titleEFICACITATEA TRATAMENTULUI LEUCEMIEI ACUTE PROMIELOCITARE LA COPII ŞI ADULŢIen_US
dc.title.alternativeEffective treatment of acute promyelicytic leukemia in children and adultsen_US
dc.typeArticleen_US
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