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Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/20669
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dc.contributor.authorNegru, I.-
dc.date.accessioned2022-05-10T07:00:44Z-
dc.date.available2022-05-10T07:00:44Z-
dc.date.issued2017-
dc.identifier.citationNEGRU, I. In vivo evaluation of xenogeneic acellular bovine fascia grafts in the reconstruction of abdominal wall defects in swine experimental model. In: Moldavian Journal of Pediatric Surgery. 2017, no. 1, pp. 66-70. ISSN 2587-3229.en_US
dc.identifier.issn2587-3210-
dc.identifier.issn2587-3229-
dc.identifier.urihttps://sncprm.info.md/journal-
dc.identifier.urihttp://repository.usmf.md/handle/20.500.12710/20669-
dc.description.abstractIn this study autor purpose to evaluate the feasibility of using bovine fascia in the experimental substitution of the fascial plan for the reconstruction of major anterior abdominal wall defects in the experimental model. Plastic reconstruction of the surgically induced abdominal wall defect using decellularized bovine fascia grafts was performed on 5-week-old Landrace pigs (3 animals) in which the abdominal wall defect of 10x5.0 cm was surgically induced with the involvement of all layers, including the peritoneum. The animals were subsequently euthanized 90 days after the intervention. For decellularization, sterile 0.5% SDS solution (HiMedia) was used in volume required to obtain acellular tissues. The solution was changed every 24 hours for 72 hours. The preventive results of the histopathological examination allowed the author to conclude that the use of decellularized bovine fascia grafts in the experimental model is characterized by the dominance of active regenerative processes with tissue remodeling and host cell invasion, the xenogeneic implant tissues being subjected to gradual degradation and substituted with the neoformed host connective tissue, the rationale of the usefulness of this biological material requiring additional comparative and clinical immunological studies. The results of this experimental study allow us to conclude the following that the usage of bovine fascia acellular grafts as an alternative xenogeneic biological implant in reconstructive surgery of abdominal wall defects, this option requiring additional comparative and clinical immunological studies.en_US
dc.language.isoenen_US
dc.publisherNational Society of Pediatric Surgery of the Republic of Moldovaen_US
dc.relation.ispartofMoldavian Journal of Pediatric Surgeryen_US
dc.subjectbioimplanten_US
dc.subjectacellular graftsen_US
dc.subjectbovine fasciaen_US
dc.subjectreconstructive surgeryen_US
dc.titleIn vivo evaluation of xenogeneic acellular bovine fascia grafts in the reconstruction of abdominal wall defects in swine experimental modelen_US
dc.typeArticleen_US
Appears in Collections:Moldavian Journal of Pediatric Surgery No. 1 2017

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