USMF logo

Institutional Repository in Medical Sciences
of Nicolae Testemitanu State University of Medicine and Pharmacy
of the Republic of Moldova
(IRMS – Nicolae Testemitanu SUMPh)

Biblioteca Stiintifica Medicala
DSpace

University homepage  |  Library homepage

 
 
Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/21028
Full metadata record
DC FieldValueLanguage
dc.contributor.authorJosan, Tatiana
dc.date.accessioned2022-06-12T10:16:56Z
dc.date.available2022-06-12T10:16:56Z
dc.date.issued2022
dc.identifier.citationJOSAN, Tatiana. Adrenal tumors in children. In: MedEspera: the 9th International Medical Congress for Students and Young Doctors: abstract book. Chișinău: S. n., 2022, p. 263.en_US
dc.identifier.urihttps://medespera.asr.md/en/books
dc.identifier.urihttp://repository.usmf.md/handle/20.500.12710/21028
dc.description.abstractIntroduction. Adrenal tumors in children are generally rare. It can be one person from 1,000.000. The most frequent type of adrenal tumor in children is neuroblastoma, with an incidence of 58 from 1,000,000 newborns of registered cases per year, about 20% of neonatal cancers, and about 8% of all childhood cancers. On the second place among tumors of the adrenal gland in children are adrenocortical tumors, which could be developed from latent congenital adrenal hyperplasia. Adrenocortical cancer accounts for 0.5% of all malignancies in children. Pheochromocytomas, which are located in the adrenal gland in children, are rare (10% of all Pheochromocytomas), but in more than 10% of cases, it is bilateral and hereditary. Generally, there aren't known concrete causes of these tumors, thus isn't a known method to reduce the risk of development of adrenal tumors. Aim of study. Studying the clinical, paraclinical particularities and the results of surgical and pharmaceutical treatment for all types of Adrenal Tumors in children, in order to highlight the most common clinical features and the best option of treatment depending on the type of Adrenal Tumor. Methods and materials. This study included 13 patients aged 4-11 years with Neuroblastomas and 1 patient with Ganglioneuroblastoma, who were treated in 2018-2021 in the Department of Pediatric Oncology of the Oncological Institute of Moldova. Also the study included 6 patients aged 0-18 years with Neuroblastomas and Pheochromocytomas who were treated in 2019-2021 in the Institute of Mother and Child Health Care. Results. Patients by gender distribution: 9 girls (45%) and 11 boys (55%). Clinically, the most common of all patients was a palpable mass in the abdomen hard and unmovable. Other clinical features include abdominal enlargement from hepatomegaly due to liver metastases - 1 patient (5%), insignificant weakness 2 patients (10%), and asymptomatic - 17 patients (85%). Of all the patients, only 4 of them have no metastasis (20%), and 16 patients have metastasis in regional lymph nodes, liver, or bones (80%). The diagnosis of adrenal mass was established postnatal in 100% of cases, and after the biopsy: 1 patient has Ganglioneuroblastoma (5%), 1 patient has Pheochromocytoma (5%), and 18 patients have Neuroblastomas (90%). Four patients received surgical treatment of total tumor excision, and one patient with a subtotal ablation. These patients underwent combined treatment and the rest of the patients - adjuvant therapy with Etoposide 30 mg + Carboplatin 150 mg, Doxorubicin 9 mg + Carboplatin 150 mg + Cyclophosphamide 300 mg or Etoposide 30 mg + Cyclophosphamide 300 mg. Conclusion. Neuroblastoma is the most common tumor from all types of adrenal tumors in children. The treatment is adjusted according to the type of tumor, stage, and eligibility criteria. The prognosis of ganglioneuroblastoma is relatively good, of the Pheochromocytoma also good with the surgical treatment, and the prognosis for Neuroblastoma is reserved. The results and prognosis can be better after combined therapy but on patients without metastasis and major laboratory changes.en_US
dc.language.isoenen_US
dc.publisherNicolae Testemitanu State University of Medicine and Pharmacy of the Republic of Moldova, Association of Medical Students and Residentsen_US
dc.relation.ispartofMedEspera: The 9th International Medical Congress for Students and Young Doctors, May 12-14, 2022, Chisinau, Republic of Moldovaen_US
dc.titleAdrenal tumors in childrenen_US
dc.typeOtheren_US
Appears in Collections:MedEspera 2022

Files in This Item:
File Description SizeFormat 
Adrenal_tumors_in_children.pdf84.29 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

 

Valid XHTML 1.0! DSpace Software Copyright © 2002-2013  Duraspace - Feedback