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Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/3988
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dc.contributor.authorAmbros, Ala
dc.contributor.authorLisii, Leonid
dc.contributor.authorBobcov, Svetlana
dc.contributor.authorProtopop, Svetlana
dc.contributor.authorTabac, Radu
dc.date.accessioned2019-06-25T11:34:59Z-
dc.date.available2019-06-25T11:34:59Z-
dc.date.issued2010
dc.identifier.citationAMBROS, Ala, LÎSÎI, Leonid et al. Aterotromboza. In: Anale Științifice ale USMF “Nicolae Testemiţanu”. Ed. a 11-a. Chișinău: CEP Medicina, 2010, vol. 1: Probleme medico-biologice si farmaceutice, pp. 248-254.en_US
dc.identifier.urihttp://repository.usmf.md/handle/20.500.12710/3988-
dc.descriptionCatedra Biochimie şi Biochimie clinică USMF ,,Nicolae Testemiţanu”en_US
dc.description.abstractThere are a lot of modifications in arterial wall in atherosclerosis; the most important is the phenomenon of thrombosis. The formation of thrombus is determined by the action of two groups of factors: the first- homeostatic independent factors (superficial erosion and rupture of fibrous cap), the second group-modifications in homeostasis: endothelial dysfunction, modifications in fibrinolysis, decrease of natural inhibitors, increase of some coagulation factors, platelets hyperactivity. Evolution of mural thrombus presents a risk for cerebral accidents, myocardial infarction, peripheral manifestations of ischemia. În patologia aterosclerotică sunt înregistrate un şir de modificări locale ale peretelui vascular, cea mai importantă fiind formarea trombului mural. Instalarea lui are loc sub acţiunea factorilor homeostatici independenţi - eroziunea şi fisurarea plăcii, expunerea componentelor înalt trombogene cât şi a modificărilor homeostaziei locale- disfuncţia endotelială şi a sistemului fibrinolitic, scăderea ponderii inhibitorilor naturali, creşterea concentraţiei unor factori ai coagulării, hiperactivitate trombocitară. Evoluţia trombului se manifestă prin accidente cerebrale, infarct miocardic, ischemie periferică dar poate decurge şi asimptomatic.en_US
dc.language.isoroen_US
dc.publisherCEP Medicinaen_US
dc.titleAterotrombozaen_US
dc.title.alternativeAtherothrombosisen_US
dc.typeArticleen_US
Appears in Collections:Biochimie și genetică

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