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Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/4136
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dc.contributor.authorŞoric, Gabriela
dc.contributor.authorGroppa, Liliana
dc.contributor.authorBecheanu, Natalia
dc.date.accessioned2019-06-25T12:51:30Z-
dc.date.available2019-06-25T12:51:30Z-
dc.date.issued2010
dc.identifier.citationŞORIC, Gabriela, GROPPA, Liliana, BECHEANU, Natalia. Axele principale în patogenia artritei reactive urogenitale. In: Anale Științifice ale USMF “Nicolae Testemiţanu”. Ed. a 11-a. Chișinău: CEP Medicina, 2010, vol. 3: Probleme actuale în medicina internă, pp. 57-62.en_US
dc.identifier.urihttp://repository.usmf.md/handle/20.500.12710/4136-
dc.descriptionCatedra Medicină Internă nr.1 a FR şi SC USMF „Nicolae Testemiţanu”en_US
dc.description.abstractMore trigger factors are known till this moment: the genetic factor (HLA B27, as well as there were proved the innate deficiencies of TLR 4 and NOD 2 as active actors in the host susceptibility to the infectious factors) and the infectious factor (the bacteria with the urogenital gait, described in the literature are Chlamidia trachomatis, Ureaplasma urealyticum and Micoplasma hominis). The pathway of the urogenital variant of the reactive arthritis involves the cellular and humoral immunity disturbance with the hyperimmune response to the direct invasion of the microorganism antigens in the joint or to the extraarticular infection. Axele principale în patogenia artritei reactive urogenitale. La momentul actual sunt descrise mai multe implicări trigger: factorul genetic (reprezentat de HLA B27, la fel sunt demonstrate deficienţele înnăscute ale TLR 4 şi NOD2 ca participanţi activi ai susceptibilităţii gazdei la factorii infecţioşi) şi factorul infecţios (bacteriile cu poartă de intrare urogennitală, descrise în literatura de specialitate sunt: Chlamidia trachomatis, Ureaplasma urealyticum şi Micoplasma hominis). Patogeneza variantei urogenitale al artritei reactive implică dereglarea imunităţii celulare şi umorale cu declanşarea răspunsului hiperimun la invazia directă a antigenelor microorganismelor în articulaţie sau la infecţia extraarticulară.en_US
dc.language.isootheren_US
dc.publisherCEP "Medicina"en_US
dc.subject.meshArthritis, Reactive -etiologyen_US
dc.subject.meshBacterial Infections -complicationsen_US
dc.subject.meshUrogenital Systemen_US
dc.subject.meshChlamydia Trachomatisen_US
dc.titleAxele principale în patogenia artritei reactive urogenitaleen_US
dc.title.alternativeThe main axes in the pathway of the reactive urogenital arthritisen_US
dc.typeArticleen_US
Appears in Collections:Cardiologie, reumatologie, nefrologie

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