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Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/4355
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dc.contributor.authorRotaru, Victoria
dc.contributor.authorBorş, Eleonora
dc.contributor.authorHangan, Corneliu
dc.contributor.authorCernit, Veronica
dc.date.accessioned2019-06-25T15:09:17Z-
dc.date.available2019-06-25T15:09:17Z-
dc.date.issued2011
dc.identifier.citationROTARU, Victoria, BORŞ, Eleonora, HANGAN, Corneliu, CERNIT, Veronica. Corelaţii dintre activitatea sistemului citokinic şi proteina C–reactivă pe parcursul şocului hemoragic. In: Anale ştiinţifice ale USMF “Nicolae Testemiţanu”. Ed. a 12-a. Chişinau: СEP Medicina, 2011, vol. 1: Probleme medico-biologice şi farmaceutice, pp. 257-262.en_US
dc.identifier.urihttp://repository.usmf.md/handle/20.500.12710/4355-
dc.descriptionCatedra Fiziopatologie şi fiziopatologie clinicăen_US
dc.description.abstractHemorrhagic shock takes place by local and systemic inflammatory processes. A pathogenetic factor of systemic inflammation is acute-phase response. During the acute-phase response, the liver dramatically increases the synthesis of acute-phase proteins, such as fibrinogen and C-reactive protein (CRP). CRP is recognized as a true marker of local and diffuse inflammatory process. Elevated levels of this protein of acute inflammation during hemorrhagic shock are caused by elevated concentrations of cytokines IL-1, IL-6, TNF-α. Şocul hemoragic se desfăşoară prin procese inflamatorii locale şi sistemice. Un factor patogenetic al inflamaţiei sistemice este Răspunsul Fazei Acute (RFA). În timpul RFA în ficat creşte corelativ sinteza proteinei C- reactive (PCR), fibrinogenului, precum şi nivelul citokinelor în sânge. PCR este recunoscută drept un marker fidel al procesului inflamator local şi difuz. Valorile crescute ale acestei proteine a fazei acute a inflamaţiei pe perioada şocului hemoragic sunt determinate de concentraţiile elevate ale citokinelor IL-1-α, IL-6 şi TNF-α.en_US
dc.language.isootheren_US
dc.publisherCEP Medicinaen_US
dc.subject.meshShock, Hemorrhagic - blooden_US
dc.subject.meshShock, Hemorrhagic - immunologyen_US
dc.subject.meshCytokinesen_US
dc.subject.meshC-reactive Proteinen_US
dc.subject.meshAcute-Phase Reactionen_US
dc.subject.meshLiveren_US
dc.subject.meshBiomarkers - blooden_US
dc.subject.meshInflammationen_US
dc.titleCorelaţii dintre activitatea sistemului citokinic şi proteina C–reactivă pe parcursul şocului hemoragicen_US
dc.title.alternativeCausal correlation between systemic activity of cytokines and C- reactive protein during hemorrhagic shocken_US
dc.typeArticleen_US
Appears in Collections:Fiziologie, fiziopatologie, biofizică

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