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Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/4474
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dc.contributor.authorSamohvalov, Elena
dc.date.accessioned2019-06-25T16:11:29Z-
dc.date.available2019-06-25T16:11:29Z-
dc.date.issued2011
dc.identifier.citationSAMOHVALOV, Elena. Particularităţile lupusului eritematos sistemic asociat cu anemia. In: Anale ştiinţifice ale USMF “Nicolae Testemiţanu”. Ed. a 12-a. Chişinau: СEP Medicina, 2011, vol. 3: Probleme actuale în medicina internă, pp.146-152.en_US
dc.identifier.urihttp://repository.usmf.md/handle/20.500.12710/4474-
dc.descriptionCatedra Medicină Internă nr.3, USMF ”Nicolae Testemiţanu”en_US
dc.description.abstractWe examined 26 patients with anemia from 53 SLE patients that were included in our study. There were evaluated blood and standard immunological tests in association with erythropoietin level by ELISA test, disease activity was appreciated by SLAM. After the investigations we determined the following forms of anemia: anaemia of chronic disease (ACD) n = 9 (34. 6%), iron deficiency anaemia (AID) n = 12 (46. 1%), autoimmune hemolytic anaemia (AHA) n = 2 (7. 7%) and other causes n = 3 (11. 5%). Haematological abnormalities manifested by anemia (Нb < 100 g / l) were detected in 100% of patients, leukopenia (< 4 х 109 /l) 30.7%, lymphopenia (<1500/ mm 3 ) in 34.6%, and thrombocytopenia (< 100 х 109 /l) only in 11.5% cases. Laboratory investigations revealed immunological changes in 53.8% of examined patients, performed by detecting antiDNA-dc, ANA and aCL antibodies. Assessment of disease activity according to SLAM showed that low activity had only 3 (11.5%) patients, moderate activity was in 18 (69. 2%) patients and major activity was detected in 5 (19. 2%) patients. Anemia is a common manifestation of systemic lupus erythematosus and can be detected by simple clinical and laboratory tests. Am evaluat 26 de pacienţi cu anemie în LES din 53 pacienţi cu LES care au fost încluşi în lotul de studiu. S-au efectuat testele hematologice şi imunologice standard, s-a asociat evaluarea eritropoetinei prin metoda ELISA, aprecierea activităţii bolii s-a efectuat după SLAM. După investigaţii am întâlnit următoarele forme de anemii: anemia bolii cronice (ABC) n = 9 (34. 6%), anemia fierodificitară (AF) n = 12 (46. 1%), anemie hemolitică autoimună (AHA) n = 2 (7. 7%) şi alte cauze n = 3 (11. 5%). Modificări hematologice manifestate prin anemie (Нb < 100 g/l) au fost depistate la 100 % de pacienţi, leucopenia (< 4 х 109 /l) la 30.7%, limfopenie (<1500/ mm 3 ) la 34.6% şi trombocitopenie (< 100 х 109 /l) numai la 11.5 %. Cercetările paraclinice au pus în evidenţa modificări imunologice la 53.8% de pacienţi examinaţi, traduse prin depistarea antiADN-dc, ANA şi anticorpii aCL. Aprecierea activităţii bolii după SLAM au arătat că activitatea joasă a maladiei au avut numai 3(11.5 %) de pacienţi, activitatea moderată a fost la 18(69.2 %) de pacienţi şi activitate majoră a fost depistată la 5(19.2 %) pacienţi. Anemie este o manifestare frecventă a lupusului eritematos sistemic şi poate fi depistată prin teste simple clinice şi paraclinice.en_US
dc.language.isoroen_US
dc.publisherCEP Medicinaen_US
dc.titleParticularităţile lupusului eritematos sistemic asociat cu anemiaen_US
dc.title.alternativePeculiarieties of systemic lupus erythematosus associated with anaemiaen_US
dc.typeArticleen_US
Appears in Collections:Reumatologie

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