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Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/6577
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dc.contributor.authorCovanţev, Serghei
dc.contributor.authorCiolac, Dumitru
dc.date.accessioned2019-06-26T17:15:31Z-
dc.date.available2019-06-26T17:15:31Z-
dc.date.issued2013
dc.identifier.citationCOVANŢEV, Serghei, CIOLAC, Dumitru. The role of mast cells in type I diabetes mellitus. In: Anale ştiinţifice ale IP USMF “Nicolae Testemiţanu”. Ed. a 9-a. Chişinau: СEP Medicina, 2013, vol. 1: Probleme medico-biologice şi farmaceutice, pp. 60-64.en_US
dc.identifier.urihttp://repository.usmf.md/handle/20.500.12710/6577-
dc.descriptionScientific Advisor – MD, PhD, Associate Professor Lilian Şaptefraţi Department of Histology, Cytology and Embryology, USMF “Nicolae Testemiţanu”en_US
dc.description.abstractThe incidence of type I diabetes mellitus is rising 3-5% per year. The general prevalence of this disease ranges from 1.6 - 30.9% depending on the country. The modern field of diabetology proposes different mechanisms for development of the disorder. Still insulitis remains the main cause, ranging from 54 - 89%, confirming the autoimmune genesis of type I diabetes. Mast cells have a wide range of functions in the connective tissue that raise many questions about their putative role in type I diabetes. In this article is presented a review of studies which show mast cells involvement in the pathophysiology of diabetes. Incidenţa diabetului zaharat de tip I creştere cu 3-5% pe an. Prevalenţa generală a acestei maladii variază intre 1.6 - 30.9%, în dependenţă de ţară. Domeniul al diabetologiei contemporan propune diferite mecanisme în dezvoltarea acestei maladii. Totuşi insulită rămâne a fi cauza principală, variind intre 54 - 89%, confirmînd geneza autoimună a diabetului zaharat. Mastocitele au o gamă vastă de funcţii în ţesutul conjunctiv, care ridică multe întrebări privind rolul lor posibil în fiziopatologia diabetului zaharat de tip I. Articol prezintă revizuire de studii care leagă celulele mastocitare, cu fiziopatologia diabetului zaharat.en_US
dc.language.isoenen_US
dc.publisherCEP Medicinaen_US
dc.subject.meshDiabetes Mellitus, Type 1en_US
dc.subject.meshMast Cellsen_US
dc.subject.meshDiabetes Mellitus, Type 1 - physiopathologyen_US
dc.titleThe role of mast cells in type I diabetes mellitusen_US
dc.title.alternativeRolui celulelor mastocitare în diabetul zaharat de tip 1en_US
dc.typeArticleen_US
Appears in Collections:Morfologie

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