USMF logo

Institutional Repository in Medical Sciences
of Nicolae Testemitanu State University of Medicine and Pharmacy
of the Republic of Moldova
(IRMS – Nicolae Testemitanu SUMPh)

Biblioteca Stiintifica Medicala
DSpace

University homepage  |  Library homepage

 
 
Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/9029
Full metadata record
DC FieldValueLanguage
dc.contributor.authorLegg, J.
dc.date.accessioned2020-05-02T19:58:44Z
dc.date.available2020-05-02T19:58:44Z
dc.date.issued2012
dc.identifier.citationLEGG, J. Bronchiolitis: aetiology, pathophysiology and therapeutic management. In: Curierul Medical. 2012, nr. 3(327), p. 399. ISSN 1875-0666.en_US
dc.identifier.issn1875-0666
dc.identifier.urihttp://moldmedjournal.md/wp-content/uploads/2016/09/18.pdf
dc.identifier.urihttp://repository.usmf.md/handle/20.500.12710/9029
dc.descriptionPaediatric Respiratory Services, Southampton University Hospitals, United Kingdom, Congresul III al Medicilor de Familie din Republica Moldova, 17–18 mai, 2012, Chişinău, Republica Moldova, Conferinţa Naţională „Maladii bronhoobstructive la copii”, consacrată profesorului universitar, doctor habilitat Victor Gheţeul, 27 aprilie, Chişinău, Republica Moldovaen_US
dc.description.abstractAcute viral bronchiolitis in young infants remains a cause of substantial morbidity and health care costs. It is the most common lower respiratory tract condition and the most common reason for the hospitalization of infants. A number of respiratory viruses have been associated with acute viral bronchiolitis although respiratory syncytial virus (RSV) remains the most frequently identified virus. The majority of affected infants have a mild self-limiting disease, while others have more severe illness and require hospitalization and,sometimes,ventilatory support. Bronchiolitis has an overall mortality rate of 0.2-0.5%, with 99% of deaths occurring in developing countries. Bronchiolitis is a clinical diagnosis based on a typical pattern of rhinorrhoea, cough, poor feeding, tachypnoea, subcostal recession and auscultatory findings of wheezing and fine inspiratory crackles. There is a distinct seasonal pattern with a peak in incidences in autumn and winter. Evidence-based reviews have suggested a limited role for diagnostic laboratory or radiographic tests in typical cases of bronchiolitis. A nasopharyngeal aspirate has been identified as the most sensitive methodfor virus detection. Pulse oximetry also provides valuable information about the severity of the disease and guides subsequent management. Supportive therapy remains the major treatment option, as no other specific treatments to date haveshown to provide clinically significantbenefits. Minimal handling, oxygen supplementation, and appropriate fluid management (including nasogastric feeds if necessary) are the mainstay of therapy. Nasal suctioning can be helpful as well. Very young infants may require cardiopulmonary monitoring for apnoea. There is a wide variation in treatment for bronchiolitis, which has led to the development of evidence-based clinical practice guidelines for treatment. Bronchodilators are inconsistently used and have been advocated for certain subgroups of infants. Several large, recent trials have revealed a lack of efficacy for routine use of either bronchodilators or corticosteroids for the treatment of bronchiolitis. Preliminary evidence suggests a potential future role nebulized hypertonic saline.
dc.language.isoenen_US
dc.publisherMinisterul Sănătăţii al Republicii Moldova, Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”en_US
dc.relation.ispartofCurierul Medical: Congresul III al Medicilor de Familie din Republica Moldova, 17–18 mai, 2012, Chişinău, Republica Moldova, Conferinţa Naţională „Maladii bronhoobstructive la copii”, consacrată profesorului universitar, doctor habilitat Victor Gheţeul, 27 aprilie, Chişinău, Republica Moldova
dc.subjectbronchiolitisen_US
dc.subjectinfantsen_US
dc.subjectrespiratoryconditionen_US
dc.subject.meshBronchiolitis--diagnosisen_US
dc.subject.meshBronchiolitis--physiopathologyen_US
dc.subject.meshBronchiolitis--etiologyen_US
dc.subject.meshChilden_US
dc.titleBronchiolitis: aetiology, pathophysiology and therapeutic managementen_US
dc.typeArticleen_US
Appears in Collections:Curierul Medical, 2012, Vol. 327, Nr. 3

Files in This Item:
File Description SizeFormat 
Bronchiolitis_aetiology_pathophysiology_and_therapeutic_management.pdf104.82 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

 

Valid XHTML 1.0! DSpace Software Copyright © 2002-2013  Duraspace - Feedback