DSpace Collection:

Curierul medical. August 2015, Vol. 58, No 4

2021-09-15T14:34:07Z

Title: Curierul medical. August 2015, Vol. 58, No 4 Abstract: From its debut in 1958, the journal has striven to support the interests of Moldovan medicine concerning the new concepts of its development. The Editorial Board warmly welcomes both the readers of and the authors for the journal, all those who are enthusiastic in searching the new and more effective ways of solving numerous medical problems. We hope that those who want to make their contribution to the science of medicine will find our journal helpful and encouraging. The journal is accredited by the National Council for Accreditation and Attestation. The journal publishes official papers, scientific articles, editorials, clinical studies and cases, lectures, methodological guides, reviews, brief reports, and correspondence. The journal welcomes articles in English, Romanian and Russian. The journal editorial policy provides the prompt publication of papers within 12 weeks after receiving them.; De la prima apariţie în 1958, revista susţine şi dezvoltă noile idei în domeniul medicinii, în Republica Moldova. Colegiul de redacţie agrează cu multă consideraţie atât cititorii cât şi autorii articolelor, pe toţi acei care cu mult entuziasm caută noi şi mult mai efective metode de soluţionare a multiplelor probleme ale medicinii. Sperăm, că toţi acei care doresc să-şi aducă aportul la dezvoltarea ştiinţelor medicale, vor găsi revista noastră utilă şi atractivă. Revista este acreditată de către Consiliul Naţional de Acreditare şi Atestare. Revista publică comunicări oficiale şi, totodată, sunt editate diverse publicaţii, inclusiv independente: articole ştiinţifice, editoriale, cercetări şi prezentări de cazuri clinice, prelegeri, îndrumări metodice, articole de sinteză, relatări scurte, corespondenţe şi recenzii. Revista publică articole în limba engleză, română şi rusă. Politica de editare a revistei prevede examinarea operativă și publicarea articolelor timp de 12 săptămâni după înaintare.; С первого дня своего выпуска в 1958 году журнал стремится поддерживать и развивать новые идеи в области медицины в Молдове. Редакционная коллегия всегда рада как читателям, так и авторам статей, всем тем, кто с энтузиазмом ищет новые, более эффективные способы решения многочисленных задач медицины. Мы надеемся, что все те, кто хотят внести свой вклад в медицинскую науку, найдут наш журнал полезным и вдохновляющим. Журнал аккредитован Высшей Аттестационной Комиссией Республики Молдова. В журнале печатаются официальные материалы, научные статьи, наблюдения из клинической практики, обобщающие статьи, краткие сообщения, методические указания, рецензии и корреспонденция. В журнале публикуются статьи на английском, румынском и русском языках. Издательская политика журнала предусматривает оперативное рассмотрение и публикацию статей в среднем в течение 12 недель после поступления. Description: Fondatori: Ministerul Sănătăţii al Republicii Moldova, Universitatea de Stat de Medicină şi Farmacie “Nicolae Testemiţanu”

Retroorbital pain and autonomic dysfunctions in patients with migraine

2021-09-15T14:35:19Z

Title: Retroorbital pain and autonomic dysfunctions in patients with migraine Authors: Curca, C. Abstract: Background. A part of migraine patients complain of unilateral or bilateral ocular pain during migraine access, which may be associated with some vegetative disorders: ptosis, mydriasis, conjunctival congestion, photo and phonophobia, lacrimation, unvoluntary periorbital muscle contractions, nasal hypersecretion. It is important to analyze the frequency of ocular pain in patients with migraine, laterality, character and their association with other autonomic manifestations. Material and methods: 91 patients with migraine (9.9% men, 90.1% women), out of them 51.6% with chronic migraine, 34.1% with episodic migraine and 14.3% with rare episodic migraine. Patients’ age was 18-63 years. The study included only patients with migraine without other associated neurological or ocular pathology. Ophthalmologic examination included assessment of visual acuity, perimetry, intraocular pressure measurement in migraine crisis and lucid period (air-push N 10-21 mm Hg), ophthalmoscopy, biomicroscopy, refractometry if necessary. Results: According to the statistical analysis of data, 48.4% patients had bilateral ocular pain during migraine attack; 26.3% unilateral headache and eye pain, 25.3% did not experience pain during the migraine attack. By the type of eye pain 34.1% had non-pulsating retro-orbital pain; 18.7% –pulsating retroorbital pain; 22% - had superficial eye pain. During the migraine attack 18.7% of migraine patients had unilateral conjunctival congestion, ipsilateral of headache; 33% bilateral congestion and congestion absent in 48.4% patients. Unilateral lacrimation – 11.4%, bilateral lacrimation in – 25.6%. Photophobia between attacks of migraine accounted for 38.6% of patients. Unilateral ptosis – 8.4% during the attack, bilateral ptosis – 10.8%. Periorbital muscle tics during the migraine attacks were observed in 42.2% patients. We found a statistically significant correlation (P <0.001) between the type of eye pain and intraocular pressure values measured during the migraine attacks and between them. Conclusions: Migraine attacks are often associated with different character of ocular pain, autonomic disorders and with increasing of intraocular pressure. Description: Institute of Neurology and Neurosurgery, Department of Ophthalmology Nicolae Testemitsanu State University of Medicine and Pharmacy, Chisinau, the Republic of Moldova

The role of microflora in the pathogenesis of burns in different climatic conditions

2024-02-02T13:42:58Z

Title: The role of microflora in the pathogenesis of burns in different climatic conditions Authors: Babiuc, Vasile Abstract: Background: In all the patients with combustions comprising more than 50% of the body surface, bacteremia takes place, and, during the shock period, its influence is minimal, then, during the toxemia period, when the autolysis process occurs in the affected area, microflora presents a particular danger. Microflora manifests its virulence completely depending on the state of the local and general immunity, which, in its turn, differs in different climatic conditions. Therefore, in order to determine the effective treatment, it is very necessary to study the microflora in patients with combustions in different diametrically opposed climatic conditions – tropical and continental. Material and methods: The investigations were performed in 287 patients with combustions in tropical conditions (Cuba) and in 133 patients with combustions in continental conditions (Moldova, Moscow) in order to determine the role of microflora in the evolution of combustions in different climatic conditions. The following factors were determined: the microbial type, the sensibility degree to antibiotics, the conditions of favoring microbial invasion and the role of the medical staff in favoring patients with combustions affected by the microbial invasion. Results: The obtained results showed that the conditions of the tropical climate are very favorable for microflora evolution, and the medical staff plays a very important role in favoring the microbial invasion, in the assessment of septicemia and also in the assessment of the microbial invasions in the pathogenesis of the combustion wounds. Conclusions: Microflora presents a very big danger in the evolution of combustions. The virulence of microflora in the conditions of the tropical climate is much higher compared to the conditions of the continental climate. The medical staff and the necessary conditions for preserving the asepsis and antisepsis play a very important role in avoiding the microbial invasion in patients with combustions, both locally, and generally. Description: Department of Orthopedics and Traumatology, Nicolae Testemitsanu State University of Medicine and Pharmacy Chisinau, the Republic of Moldova

Evidence-based medicine – an innovative approach to clinical medicine

2021-09-15T14:35:59Z

Title: Evidence-based medicine – an innovative approach to clinical medicine Authors: Spinei, L.; Rotaru, N.; Condrea, O. Abstract: Background: Evidence-based medicine (EBM) represents an approach that integrates clinical experience and patient’s values with the best available research information. It involves a process of lifelong problem-based learning that requires a variety of new skills for medical practitioners such as efficient literature-searching, familiarity with the types of research evidence, clinical literature evaluation and evidence appraisal. The key elements of EBM such as common EBM steps that have been developed to provide an efficient framework for medical practitioners, the types of evidence and how the evidence is appraised for validity, the types of research studies and study designs as well as their corresponding levels of evidence and the “evidence pyramid”. It is necessary to increase the awareness of EBM principles among medical practitioners and pave the way to an evidence-based clinical practice. Conclusions: 1. EBM integrates the best available information with patient’s values, clinical expertise and latest research evidence; 2. A significant progress in the practical implementation of EBM has been made by the increasing availability of EBM resources able to search, appraise and summarize the literature on a given topic; 3. An important element of external evidence and EBM are represented by the systematic reviews and meta-analyses, designed to provide relevant summaries about the best available evidence on a specific topic while minimizing the bias; 4. As a result of increasing demands for an evidencebased approach and a wider availability of information resources, EBM is gaining increasing support among the medical practitioners, optimizing their clinical decision-making, increasing their confidence and facilitating their clinical practice. Description: School of Public Health, Department of Radiology, Nicolae Testemitsanu State University of Medicine and Pharmacy, Chisinau, the Republic of Moldova