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  <title>DSpace Collection:</title>
  <link rel="alternate" href="http://repository.usmf.md:80/handle/20.500.12710/332" />
  <subtitle />
  <id>http://repository.usmf.md:80/handle/20.500.12710/332</id>
  <updated>2026-04-19T02:16:44Z</updated>
  <dc:date>2026-04-19T02:16:44Z</dc:date>
  <entry>
    <title>Analiza comparativă a particularităţilor clinice, aspectelor patogenice şi electrofiziologice ale neuropatiilor asociate limfoamelor maligne Hodgkin şi non-Hodgkin</title>
    <link rel="alternate" href="http://repository.usmf.md:80/handle/20.500.12710/24121" />
    <author>
      <name>Gherghelegiu, Evelina</name>
    </author>
    <author>
      <name>Gavriliuc, Mihail</name>
    </author>
    <author>
      <name>Corcimaru, Ion</name>
    </author>
    <id>http://repository.usmf.md:80/handle/20.500.12710/24121</id>
    <updated>2023-04-18T08:05:30Z</updated>
    <published>2011-01-01T00:00:00Z</published>
    <summary type="text">Title: Analiza comparativă a particularităţilor clinice, aspectelor patogenice şi electrofiziologice ale neuropatiilor asociate limfoamelor maligne Hodgkin şi non-Hodgkin
Authors: Gherghelegiu, Evelina; Gavriliuc, Mihail; Corcimaru, Ion
Abstract: Summary.&#xD;
Peripheral nervous system involvement due to Hodgkin and non-Hodgkin malignant&#xD;
lymphomas, register significant clinical heterogeneity. The type, severity and extension of&#xD;
nervous system impairment are appreciated by electrophysiological study. The objectives of the&#xD;
study are to analyze and compare clinical peculiarities, pathogenic aspects and&#xD;
electrophysiological patterns of neuropathies in malignant Hodgkin and non-Hodgkin&#xD;
Lymphomas.; Rezumat. Implicarea sistemului nervos periferic în limfoamele maligne Hodgkin și non-Hodgkin, înregistrează o varietate clinică semnificativă. Tipul de afectare, severitatea și extinderea leziunilor de sistem nervos periferic se apreciază electrofiziologic. Scopul studiului constă în analiza comparativă a particularităților clinice, aspectelor patogenice și electrofiziologice ale neuropatiilor asociate limfoamelor maligne Hodgkin și non-Hodgkin.</summary>
    <dc:date>2011-01-01T00:00:00Z</dc:date>
  </entry>
  <entry>
    <title>Tumori maligne multiple la pacienţii cu limfomul Hodgkin</title>
    <link rel="alternate" href="http://repository.usmf.md:80/handle/20.500.12710/1872" />
    <author>
      <name>Oleinicova, Elena</name>
    </author>
    <id>http://repository.usmf.md:80/handle/20.500.12710/1872</id>
    <updated>2019-06-22T13:13:34Z</updated>
    <published>2011-01-01T00:00:00Z</published>
    <summary type="text">Title: Tumori maligne multiple la pacienţii cu limfomul Hodgkin
Authors: Oleinicova, Elena
Abstract: The second malignant tumours were revealed in 65 (4,2%) cases of 1549 Hodgkin’s&#xD;
disease patients. In 5 cases the concomitant development of them was present. In another 10&#xD;
cases Hodgkin’s disease was a metachronous neoplasm as to seven primary solid tumours and&#xD;
three chronic limphoprolipheratic disease. The second malignant tumours developed in 50 cases&#xD;
of Hodgkin’s disease in patients 3-30 years after being treated. Only one patient of these had&#xD;
acute myeloblastic leukemia 3,5 years after Hodgkin’s disease treatment with chemoradiotherapy.&#xD;
The second solid malignancies were present in the remaining 49 patients. Their&#xD;
localization was various.&#xD;
&#xD;
&#xD;
&#xD;
&#xD;
&#xD;
&#xD;
&#xD;
Din 1549 de cazuri de limfom Hodgkin, la 65 (4,2%) de bolnavi au fost depistate tumori&#xD;
secundare maligne. La 5 pacienţi dezvoltarea lor a fost sincronă. În 10 cazuri limfomul Hodgkin&#xD;
s-a dezvoltat metacron faţă de alte 7 tumori primare solide şi trei maladii limfoproliferative&#xD;
cronice. În 50 de cazuri tumorile secundare maligne s-au dezvoltat după 3-30 ani de la&#xD;
tratamentul limfomului Hodgkin. Numai la un pacient după 3,5 ani de la tratamentul combinat&#xD;
chimioradioterapeutic s-a diagnosticat leucemie acută mieloblastică. La ceilalţi 49 de bolnavi sau&#xD;
dezvoltat tumori secundare solide. Localizarea lor a fost variată. La 5 bolnavi s-au înregistrat&#xD;
câte 2-3 tumori secundare maligne.
Description: (şef – prof. univ. Ion Corcimaru)&#xD;
Catedra Hematologie şi Oncologie USMF “N.Testemiţanu”</summary>
    <dc:date>2011-01-01T00:00:00Z</dc:date>
  </entry>
  <entry>
    <title>Caracteristica recidivelor la pacienţii cu limfomul Hodgkin în stadiile locale</title>
    <link rel="alternate" href="http://repository.usmf.md:80/handle/20.500.12710/1871" />
    <author>
      <name>Danila, Aliona</name>
    </author>
    <author>
      <name>Robu, Maria</name>
    </author>
    <author>
      <name>Oleinicova, Elena</name>
    </author>
    <author>
      <name>Musteaţă, Larisa</name>
    </author>
    <author>
      <name>Gladâş, Valentina</name>
    </author>
    <author>
      <name>Buruiană, Sanda</name>
    </author>
    <author>
      <name>Popescu, Maria</name>
    </author>
    <id>http://repository.usmf.md:80/handle/20.500.12710/1871</id>
    <updated>2019-06-22T13:13:33Z</updated>
    <published>2011-01-01T00:00:00Z</published>
    <summary type="text">Title: Caracteristica recidivelor la pacienţii cu limfomul Hodgkin în stadiile locale
Authors: Danila, Aliona; Robu, Maria; Oleinicova, Elena; Musteaţă, Larisa; Gladâş, Valentina; Buruiană, Sanda; Popescu, Maria
Abstract: There were studied clinical peculiarities of relapses in 38 patients aged from 14-68 with&#xD;
Hodgkin’s lymphoma (LH) in local complete remission stages. It was established that&#xD;
recurrences developed more frequently in patients aged 21-40 years. The frequency of relapses&#xD;
was higher in patients with stage II of LH and in cases when primary location was in the&#xD;
mediastinum. It was observed that the later complete resolution is obtained during the treatment,&#xD;
there is the greater probability for the appearance of relapse. The relapses in patients with the&#xD;
local stages more frequently occurred within the first 2 years of complete remission with&#xD;
subsequent decrease in the following years.&#xD;
&#xD;
&#xD;
&#xD;
&#xD;
&#xD;
&#xD;
&#xD;
Au fost studiate particularităţile clinice ale recidivelor la 38 pacienţi cu limfomul&#xD;
Hodgkin în stadiile locale în virsta de la 14 pâna la 68 ani. S-a constatat că recidivele s-au&#xD;
dezvoltat mai frecvent la pacienţii în vârsta de 21-40 ani. Frecvenţa recidivelor a fost mai înaltă&#xD;
la pacienţii cu stadiul II al limfomului Hodgkin şi în cazurile localizării focarului primar în&#xD;
mediastin. S-a observat că cu cât remisiunea completă este obţinută la o etapă mai tardivă a&#xD;
tratamentului cu atât mai mare este probabilitatea apariţiei recidivelor. Recidive mai frecvent au&#xD;
apărut în primii 2 ani după obţinerea remisiunii complete cu scăderea lor ulterioară în următorii&#xD;
ani
Description: (şef – prof. univ. Ion Corcimaru)&#xD;
Catedra Hematologie şi Oncologie USMF “N.Testemiţanu”</summary>
    <dc:date>2011-01-01T00:00:00Z</dc:date>
  </entry>
  <entry>
    <title>Recidivele leucemiei acute promielocitare</title>
    <link rel="alternate" href="http://repository.usmf.md:80/handle/20.500.12710/1870" />
    <author>
      <name>Gladâş, Valentina</name>
    </author>
    <author>
      <name>Corcimaru, Ion</name>
    </author>
    <author>
      <name>Robu, Maria</name>
    </author>
    <author>
      <name>Chelea, Iurii</name>
    </author>
    <author>
      <name>Musteaţă, Vasile</name>
    </author>
    <author>
      <name>Mocanu, Irina</name>
    </author>
    <id>http://repository.usmf.md:80/handle/20.500.12710/1870</id>
    <updated>2019-06-22T13:13:33Z</updated>
    <published>2011-01-01T00:00:00Z</published>
    <summary type="text">Title: Recidivele leucemiei acute promielocitare
Authors: Gladâş, Valentina; Corcimaru, Ion; Robu, Maria; Chelea, Iurii; Musteaţă, Vasile; Mocanu, Irina
Abstract: We have followed up 67 patients with acute promyelocytic leukemia, who underwent&#xD;
combined treatment with ATRA and polychemotherapy (PCT). Complete remissions were&#xD;
achieved in 55 (82,1%) cases. Early relapses were registered in 9 (34,6%) patients. Late relapses&#xD;
developed in 17 ( 66.4%) cases, four of these patients abolished the treatment. Relapses more&#xD;
often (82,4%) develop in the patients in first 3 years of complete remision, but in following&#xD;
years the frecvency of relapses is significantly reduced.Repeated combined treatment with&#xD;
ATRA and PCT appeared to be efficient in 5 (23,8%) cases.&#xD;
Key words: Acute promyelocytic leukemia, All-trans-retinoic acid, relapse.&#xD;
&#xD;
&#xD;
&#xD;
&#xD;
&#xD;
&#xD;
&#xD;
Sub supraveghere s-au aflat 67 de bolnavi de leucemie acută promielocitară, care au&#xD;
primit tratament cu ATRA în combinaţie cu polichimioterapie. Remisiuni complete au fost&#xD;
obţinute la 55 (82,1%) bolnavi. Recidive precoce au fost constatate la 9 (34,6%) pacienţi,&#xD;
recidive tardive în 17 (66,4%) cazuri. Recidivele mai frecvent (82,4%) au aparut în primii 3 ani&#xD;
de remisiune completă, ulterior cu scăderea lor considerabilă. Remisiune completă în&#xD;
tratamentul recidivelor a fost obţinută la 5 (23,8%) bolnavi.
Description: Catedra Hematologie şi Oncologie a USMF “N.Testemiţanu”&#xD;
Instituţie Medico-Sanitară Publică Institutul de Oncologie din Moldova</summary>
    <dc:date>2011-01-01T00:00:00Z</dc:date>
  </entry>
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