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  <title>DSpace Collection:</title>
  <link rel="alternate" href="http://repository.usmf.md:80/handle/20.500.12710/482" />
  <subtitle />
  <id>http://repository.usmf.md:80/handle/20.500.12710/482</id>
  <updated>2026-04-12T09:40:02Z</updated>
  <dc:date>2026-04-12T09:40:02Z</dc:date>
  <entry>
    <title>Unele aspecte histologice, fiziopatologice şi imunologice în comportamentul agresiv al colesteatomului (Revista literaturii)</title>
    <link rel="alternate" href="http://repository.usmf.md:80/handle/20.500.12710/3841" />
    <author>
      <name>Sandul, Alexandru</name>
    </author>
    <author>
      <name>Maniuc C., Mihail</name>
    </author>
    <author>
      <name>Guţuleac, Ludmila</name>
    </author>
    <id>http://repository.usmf.md:80/handle/20.500.12710/3841</id>
    <updated>2022-06-09T08:40:04Z</updated>
    <published>2009-01-01T00:00:00Z</published>
    <summary type="text">Title: Unele aspecte histologice, fiziopatologice şi imunologice în comportamentul agresiv al colesteatomului (Revista literaturii)
Authors: Sandul, Alexandru; Maniuc C., Mihail; Guţuleac, Ludmila
Abstract: Cholesteatoma are invasive, locally destructive skin-like lesions that, after operative removal, have a significant recidivistic rate. These aggressive characteristics suggest a fundamental  alteration  in the biology of one or more of  its constituents ( keratinocytes, fibroblasts, and inflammatory cells). Although it is generally accepted that destruction and remodeling of  auditive ossicles and temporal bone  are  mainly caused by the action of osteoclasts, it has been shown that  other constituents also play a role in predigesting the osteoid layer and exposing the mineralized bone to osteoclastic activity.&#xD;
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Colesteatomul este o leziune local-distructivă de tip epitelial, care manifestă o rată recidivantă semnificativă, chiar  după  intervenţia operatorie.Proprietăţile sale agresive sugerează o alterare fundamentală  în  structura uneia din componentele sale (cheratinocite, fibroblaşti şi celule inflamatorii).Chiar dacă  este  acceptat că distrucţia şi remodelarea osişoarelor auditive şi a osului temporal, cel mai frecvent, sînt cauzate de acţiunea osteoclaştilor, a fost demonstrat şi rolul altor elemente  în degenerarea şi expunerea substanţelor organice şi osului mineralizat la acţiunea osteoclaştilor.
Description: Catedra Otorinolaringologie USMF “Nicolae Testemiţanu”</summary>
    <dc:date>2009-01-01T00:00:00Z</dc:date>
  </entry>
  <entry>
    <title>Rinita alergică şi astmul bronşic. O singură cale – o singură boală  (Revista literaturii)</title>
    <link rel="alternate" href="http://repository.usmf.md:80/handle/20.500.12710/3842" />
    <author>
      <name>Maniuc, Mihail</name>
    </author>
    <author>
      <name>Sandul, Alexandru</name>
    </author>
    <author>
      <name>Danilov, Lucian</name>
    </author>
    <author>
      <name>Pojoga, Ludmila</name>
    </author>
    <author>
      <name>Parfeni, Viorica</name>
    </author>
    <id>http://repository.usmf.md:80/handle/20.500.12710/3842</id>
    <updated>2019-06-25T10:18:59Z</updated>
    <published>2009-01-01T00:00:00Z</published>
    <summary type="text">Title: Rinita alergică şi astmul bronşic. O singură cale – o singură boală  (Revista literaturii)
Authors: Maniuc, Mihail; Sandul, Alexandru; Danilov, Lucian; Pojoga, Ludmila; Parfeni, Viorica
Abstract: Rhinitis and asthma, until recently, have been evaluated and treated as separate disorders, but nowadays opinion has moved this concept. “One way- one disease” hypothesis supposer that this two illnesses represent the manifestation of a single nosologic entity in two different parts of the human respiratory tract. Our article describes links between the upper and lower airways.&#xD;
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Interrelaţiile dintre procesele inflamatorii a căile respiratorii superioare (cavitatea nazală,  sinusurile paranazale, faringe) şi celor inferioare (bronhii şi bronhiole) prezintă interes atît din punct de vedere clinic, cît şi fiziologic. Pentru a înţelege evoluţia patologiei care aparent afectează un singur etaj al sistemului respirator e nevoie de a analiza funcţia acestui sistem integru, ceea ce ne dă posibilitatea de a vizualiza influenţa acestei patologii asupra activităţii întregului sistem, cît şi vice-versa.
Description: Catedra Otorinolaringologie a USMF „Nicolae Testemiţanu”</summary>
    <dc:date>2009-01-01T00:00:00Z</dc:date>
  </entry>
  <entry>
    <title>Tratamentul complicaţiilor otogene în SCR de copii „E. Coţaga” în anii 1996- 2008</title>
    <link rel="alternate" href="http://repository.usmf.md:80/handle/20.500.12710/3843" />
    <author>
      <name>Danilov, Lucian</name>
    </author>
    <author>
      <name>Maniuc, Mihail</name>
    </author>
    <author>
      <name>Pojoga, Ludmila</name>
    </author>
    <author>
      <name>Nicolaenco, Tatiana</name>
    </author>
    <id>http://repository.usmf.md:80/handle/20.500.12710/3843</id>
    <updated>2019-06-25T10:18:59Z</updated>
    <published>2009-01-01T00:00:00Z</published>
    <summary type="text">Title: Tratamentul complicaţiilor otogene în SCR de copii „E. Coţaga” în anii 1996- 2008
Authors: Danilov, Lucian; Maniuc, Mihail; Pojoga, Ludmila; Nicolaenco, Tatiana
Abstract: Complications of otitis media are much more rare today due to the presence of prompt antibiotic treatment of otitis media. However, the morbidity and mortality rates remain high. In our study we assessed the frequency of complications of otitis media in children admitted to the ENT clinic of Children Republican Hospital „E. Coţaga”between 1996 and 2008. We analysed statistical data of this pathology and the results of treatment. The most frequent complications were mastoiditis.&#xD;
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Datorită introducerii în tratamentul otitelor medii a antibioticelor, incidenţa complicaţiilor otogene, în prezent s-a redus. Necătînd la aceasta, totuşi rata morbidităţii şi mortaliţii rămîne a fi înaltă. În acets studiu, noi am analizat frecvenţa complicaţiilor otogene la copiii internaţi în clinica ORL a SCRC „E. Coţaga”, între anii 1996- 2008. S-a efectuat o statistică a patologiei menţionate şi s-a analizat rezultatele tratamentului. Cea mai frecvent întîlnită complicaţie otogenă este mastoidita.
Description: Catedra Otorinolaringologie a USMF „Nicolae Testemiţanu”&#xD;
Clinica Otorinolaringologie SCR de copii „Em. Coţaga”</summary>
    <dc:date>2009-01-01T00:00:00Z</dc:date>
  </entry>
  <entry>
    <title>Unele aspecte ale patogenezei schimbărilor funcţionale a glandei tiroide asociate cu tonsilită cronică (Revista literaturii)</title>
    <link rel="alternate" href="http://repository.usmf.md:80/handle/20.500.12710/3840" />
    <author>
      <name>Sandul, Alexandru</name>
    </author>
    <author>
      <name>Baltag, Natalia</name>
    </author>
    <author>
      <name>Capitan, Nina</name>
    </author>
    <author>
      <name>Eşanu, Ruslan</name>
    </author>
    <id>http://repository.usmf.md:80/handle/20.500.12710/3840</id>
    <updated>2019-06-25T10:18:59Z</updated>
    <published>2009-01-01T00:00:00Z</published>
    <summary type="text">Title: Unele aspecte ale patogenezei schimbărilor funcţionale a glandei tiroide asociate cu tonsilită cronică (Revista literaturii)
Authors: Sandul, Alexandru; Baltag, Natalia; Capitan, Nina; Eşanu, Ruslan
Abstract: Inflammatory diseases of lymphatic  ring paryngs represents one of the leading places in the general structure of ORL-organs pathology. Autoimmun processes, occurring in lymphoid tissue of palatal tonsils develops  system complications and negativly influenced on  their pathogenesis. This is article reflects some aspects of functional changes from thyroid gland associated with chronic tonsillitis, which can proceed on hyper- and hypo- function type.&#xD;
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Inflammatory diseases of lymphatic  ring paryngs represents one of the leading places in the general structure of ORL-organs pathology. Autoimmun processes, occurring in lymphoid tissue of palatal tonsils develops  system complications and negativly influenced on  their pathogenesis. This is article reflects some aspects of functional changes from thyroid gland associated with chronic tonsillitis, which can proceed on hyper- and hypo- function type.
Description: Catedra Otorinolaringologie a USMF „Nicolae Testemiţanu”&#xD;
Secţia Endocrinologie a SCM „Sf. Treime”</summary>
    <dc:date>2009-01-01T00:00:00Z</dc:date>
  </entry>
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