DSpace Collection:http://repository.usmf.md:80/handle/20.500.12710/6002026-04-22T15:46:32Z2026-04-22T15:46:32ZTaraxacum officinale roots acts as a powerful antioxidantFulga, AlaProtopop, SvetlanaGudumac, ValentinTagadiuc, Olgahttp://repository.usmf.md:80/handle/20.500.12710/231242022-12-05T11:59:18Z2022-01-01T00:00:00ZTitle: Taraxacum officinale roots acts as a powerful antioxidant
Authors: Fulga, Ala; Protopop, Svetlana; Gudumac, Valentin; Tagadiuc, Olga2022-01-01T00:00:00ZThe effects of controlled reperfusion on oxidative lesions in ovarian torsionLazăr, Corneliahttp://repository.usmf.md:80/handle/20.500.12710/130612020-12-17T11:05:18Z2020-01-01T00:00:00ZTitle: The effects of controlled reperfusion on oxidative lesions in ovarian torsion
Authors: Lazăr, Cornelia
Description: VII International
medical and pharmaceutical congress
of students and young scientists, Chernivtsi, 20202020-01-01T00:00:00ZAre nowadays laboratory indices useful in ovarian torsion?Lazăr, Corneliahttp://repository.usmf.md:80/handle/20.500.12710/130602020-12-17T11:04:33Z2019-01-01T00:00:00ZTitle: Are nowadays laboratory indices useful in ovarian torsion?
Authors: Lazăr, Cornelia
Description: VII International medical and pharmaceutical congress
of students and young scientists, Chernivtsi, 20192019-01-01T00:00:00ZControlled reperfusion and oxidative stress-induced lesions in experimental ovarian torsion/detorsionLazăr, CorneliaTagadiuc, O.Misina, A.Vozian, M.Pantea, V.http://repository.usmf.md:80/handle/20.500.12710/130592020-12-17T11:04:57Z2017-01-01T00:00:00ZTitle: Controlled reperfusion and oxidative stress-induced lesions in experimental ovarian torsion/detorsion
Authors: Lazăr, Cornelia; Tagadiuc, O.; Misina, A.; Vozian, M.; Pantea, V.
Abstract: Ovarian torsion (OT), being a medical emergency,
requires being correctly treated in the early stages of the
disease, because reperfusion (R) injury may worsen
existing lesions, leading to ovarian loss.
The purpose of our study was to investigate the
advanced oxidation protein products (AOPP) changes in
rats’ serum subjected to different OT/detorsion models.
Materials and methods. 70 healthy female rats (Rattus
albicans), were randomized into 7 groups (n=10): nr. 1:
healthy rats – no intervention; nr. 2: the sham group
(laparotomy); nr. 3, 4 and 5 – OT for 3 hours and 3 hours
ischemia with 1 hour R or 1 hour “on-off “ R; nr. 6 and 7: 3
hours OT and 24 hours R or 24 hours “on-off “ R. The “on-
off method”: controlled R by opening and closing the clips
that were applied on the ovarian annexes (on/off) in 10-
seconds intervals, for a total of 120 seconds.
AOPP level wàs measured in the blood serum samples
by Capeillère-Blandin C., et al. method (2004). The results
were analyzed by Welch’s ANOVA.
Results. A statistically significant higher AOPP
level was established in rats’ serum to 24 hours R following
OT (mean±SE, 33,23±0,59 μM/L, p=0,001), compared
with group nr. 1. The “on-off “ reperfusion method resulted
in a decrease in AOPP, 24 hours after “on-off “ reperfusion
(26,58±0,56 μM/L, p<0,001).
Conclusions: “On-off” method of R minimizes the
reperfusion injury in OT.
Description: Department of Biochemistry and Clinical
Biochemistry, “Nicolae Testemitanu” State University of
Medicine and Pharmacy Chisinau, Republic of Moldova;
Department of Biochemistry and Clinical Biochemistry,
“Nicolae Testemitanu” State University of Medicine and
Pharmacy Chisinau, Republic of Moldova;
Department of Surgical Gynecology, Mother and Child
Institute Chisinau, Republic of Moldova;
Department of Surgery nr.1 “Nicolae Anestiadi”,
“Nicolae Testemitanu” State University of Medicine and
Pharmacy Chisinau, Republic of Moldova;
Laboratory of Biochemistry, “Nicolae Testemitanu”
State University of Medicine and Pharmacy
Chisinau, Republic of Moldova.2017-01-01T00:00:00Z