http://repository.usmf.md:80/handle/20.500.12710/671 2026-04-23T05:08:46Z 2026-04-23T05:08:46Z Данила, А.Н. http://repository.usmf.md:80/handle/20.500.12710/21310 2022-06-25T11:31:29Z 2016-01-01T00:00:00Z

Title: Характер рецидивов после комбинированного лечения лимфомы Ходжкина I–II стадии Authors: Данила, А.Н.

2016-01-01T00:00:00Z Golub, Aliona Robu, Maria http://repository.usmf.md:80/handle/20.500.12710/21309 2022-06-25T11:22:55Z 2018-01-01T00:00:00Z

Title: Manifestările clinice şi frecvenţa recăderilor la pacienţii cu limfom Hodgkin, stadiile locale (I-II) Authors: Golub, Aliona; Robu, Maria Abstract: Clinical manifestations and frequency of relapses were studied in 90 patients, aged 18-79 years, with Hodgkin’s lymphoma (HL), classical type, stages I and II, with complete remission after the first-line treatment. The diagnosis in all cases was morphologically confirmed. It was found that HL developed more frequently in people aged 18-39 years (76.7%). In 55.5% cases, the diagnosis was established within the first 3 months of the first manifestation of the disease.The onset of HL, classical type, occurred more frequently in the mediastinum (42.3%) and supraclavicular lymph nodes (33.3%). The frequency of recurrence accounted for 24.4%. Relapses occurred more frequently in cases of primary involvement of the mediastinum and supraclavicular lymph nodes (26.3% and 26.7%, respectively), depending on the tumor size. Relapses were recorded more frequently in HL cases with large tumors.; Изучены клинические проявления и частота рецидивов у 90 больных с полными ремиссиями лимфомы Ходжкина в I – II стадиях в возрасте от 18 до 79 лет. Диагноз во всех случаях был подтверждён при морфологическом исследовании. Установлено, что лимфому Ходжкина чаще диагностировали в возрасте от 18 до 39 лет (76,7%). Первичный опухолевый очаг чаще располагался в средостенных (42,3%) и надключичных (33,3%) лимфатических узлах. Частота рецидивов составила 24,4%. Рецидивы чаще наблюдали при локализации первичной опухоли в средостенных (26,3%) и надключичных (26,7%) лимфатических узлах. Частота рецидивов коррелировала с раз-мерами первичной опухоли. В случаях больших размеров опухолей частота рецидивов возрастала.; Au fost studiate manifestările clinice şi frecvenţa recăderilor la 90 de pacienţi cu limfom Hodgkin (LH), forma clasică, stadiile I şi II cu remisiuni complete obţinute după tratamentul de prima linie cu vârsta cuprinsă între 18 şi 79 ani. Diagnosticul în toate cazurile a fost confirmat morfologic. S-a constatat că LH s-a dezvoltat mai frecvent la persoanele cu vârsta de 18-39 de ani (76,7%). Debutul LH, forma clasică a avut loc mai frecvent în mediastin (42,3%) şi în gangli-onii limfatici supraclaviculari (33,3%). Frecvenţa recăderilor a constituit 24,4%. Recăderile au avut loc mai frecvent în cazurile de afectare primară a mediastinului, ganglionilor limfatici supraclaviculari (26,3% şi 26,7%, respectiv) şi au fost în funcţie de dimensiunile tumorii. Recăderile au fost înregistrate mai frecvent în cazurile LH cu dimensiunile mari ale tumorii.

2018-01-01T00:00:00Z