http://repository.usmf.md:80/handle/20.500.12710/16081 2026-04-07T14:45:31Z http://repository.usmf.md:80/handle/20.500.12710/16256 Title: The Moldovan Medical Journal. April 2017, Vol. 60, No 2 Abstract: The journal was founded in 1958 on the initiative of Nicolae Testemitsanu, an outstanding expert in orthopedics, social medicine, and public health. Now the publisher of the journal is the Scientific Medical Association of Moldova and the journal has become the scientific peer-reviewed periodical Edition designed for specialists in the areas of medicine, dentistry, pharmacy, social medicine, and public health. From its debut the journal has striven to support the interests of Moldovan medicine concerning the new concepts of its development. The aim of the Moldovan Medical Journal is to provide the international community with the results of scientific researches performed in the medical institutions of Moldova and inform Moldovan medical society about the advanced achievements of medicine abroad. The Editorial Board warmly welcomes both the readers of and the authors of the journal, all those who are enthusiastic about searching for new and more effective ways of solving numerous medical problems. We hope that those who want to make their contribution to the science of medicine will find our journal helpful and encouraging. Description: Fondatori: Ministerul Sănătăţii al Republicii Moldova, Universitatea de Stat de Medicină şi Farmacie “Nicolae Testemiţanu” 2017-01-01T00:00:00Z http://repository.usmf.md:80/handle/20.500.12710/14061 Title: Monograph “Pituitary adenomas. Morphopathology and molecular profile”, the author: Eugen Melnic Authors: Vataman, Vladimir Description: Department of Morphopathology, Nicolae Testemitsanu State University of Medicine and Pharmacy, Chisinau, the Republic of Moldova 2017-01-01T00:00:00Z http://repository.usmf.md:80/handle/20.500.12710/2720 Title: Radiofrequency ablation – new insights into the modern treatment of atrial flutter and fibrillation Authors: Grib, Liviu; Cenusa, Octavian; Varvariuc, Viorica; Abraș, Marcel; Grib, Andrei; Grajdieru, Romeo Abstract: Background: Atrial fibrillation (AF) is associated with a 5-fold increase in the risk of stroke and a 3-fold increase in the incidence of heart failure. The increase in AF prevalence can be attributed both to better detection of silent AF, alongside increasing age and conditions predisposing to AF. Nonpharmacological measures aimed at «healing» AF were initially tested in open surgery. Searching for an approach with a greater chance of success led to the development of radiofrequency ablation (RFA). Only recently RFA technique began to be used extensively in people with AF, not being tested in large randomized studies, with establishment of remote results. Conclusions: Catheter ablation is used successfully in patients suffering from symptomatic paroxysmal atrial fibrillation, as an alternative to drug therapy. Performed correctly by a trained and experienced electrophysiolologist, RFA allows us to get remarkable results, being possible suspension of treatment with antiarrhythmic drugs and to avoid its so well known side’s effects. RFA with catheter is superior to antiarrhythmic drug therapy in preventing recurrence in both persistent AF and in the paroxysmal AF. The success rate of RFA in experienced centers for paroxysmal AF exceeds 70% a year. RFA reintervention is necessary in the approximately 9-20% of patients with more modest results. The frequency of major complications related to RFA is less than 5%. The restored sinus rhythm with RFA in patients with heart failure may be associated with significant improvement in left ventricular ejection fraction. Description: Department of Internal Medicine, Medical clinic No 3, Discipline of Cardiology, Nicolae Testemitsanu State University of Medicine and Pharmacy, Chisinau, the Republic of Moldova 2017-01-01T00:00:00Z http://repository.usmf.md:80/handle/20.500.12710/2718 Title: Intrauterine growth restriction: contemporary issues in diagnosis and management Authors: Capros, Hristiana; Scoricova, Iana; Mihalcean, Luminita Abstract: Background: Intrauterine growth restriction represents a fetal life treating condition in obstetrics. Diagnosis and appropriate management during pregnancy is essential because of the considerable morbidity and mortality to which restricted new-borns are exposed. Implementation of diagnostic criteria could potentially determine an optimized outcome in these patients. Material and methods: The article reflects a study of 728 cases of patients delivered to the Obstetrical department of Municipal Hospital No1, Chisinau, the Republic of Moldova during January-December 2016. A special protocol for clinical and paraclinical data collection was used. From these 728 cases, 50 histories of low birth weight fetuses (<2500g) were analysed in detail. Results: The average weight of LBW fetuses was 2057 gr. 27 fetuses (54%) were diagnosed as intrauterine growth restricted fetuses. The average weight of fetuses with the diagnosis of IUGR was 1989 gr. 18.52% infants had a very low birth weight (1000-1499 g.), 84.48% infants had low birth weight (2500-1500 g). Conclusions: The prevalent criteria for diagnosis of intrauterine growth restriction in our study were foetal abdominal circumference below 10th percentile (52.3 %). The ultrasound evaluation showed to have an average sensitivity in the predicting the foetal weight at birth (47.6%). In the majority of cases the delivery was done by cesarian section (62.9%), with the most frequent indication for foetal extraction – vascular redistribution and beginning of cerebral vasodilatation (37.5 %). Description: Department of Obstetrics and Gynecology, Nicolae Testemitsanu State University of Medicine and Pharmacy, Chisinau, the Republic of Moldova 2017-01-01T00:00:00Z