http://repository.usmf.md:80/handle/20.500.12710/16707 2026-04-10T14:04:23Z http://repository.usmf.md:80/handle/20.500.12710/17856 Title: Buletin de perinatologie. 2017, Nr. 4(76) Abstract: Revistă științifico–practică. Fondată în anul 1998. Description: Fondatori: Institutul Mamei și Copilului, Societatea de Pediatrie din Republica Moldova 2017-01-01T00:00:00Z http://repository.usmf.md:80/handle/20.500.12710/17676 Title: În grabă de a face bine, în memoria profesorului universitar, doctor habilitat în medicină Constantin Eţco, 22.07.1941-19.12.2017 Authors: Holban, Ion Description: Consiliului Naţional pentru Acreditare şi Atestare 2017-01-01T00:00:00Z http://repository.usmf.md:80/handle/20.500.12710/17675 Title: Evaluating progestogens for prevention of preterm birth international collaborative (EPPPIC) individual participant data (IPD) meta-analysis: protocol Authors: Stewart, Lesley A.; Simmonds, Mark; Duley, Lelia; Dietz, Kristina Charlotte; Harden, Melissa; Hodkinson, Alex; Llewellyn, Alexis; Sharif, Sahar; Walker, Ruth; Wright, Kath Abstract: Background: Preterm birth is the most common cause of death and harm to newborn babies. Babies that are born early may have difficulties at birth and experience health problems during early childhood. Despite extensive study, there is still uncertainty about the effectiveness of progestogen (medications that are similar to the natural hormone progesterone) in preventing or delaying preterm birth, and in improving birth outcomes. The Evaluating Progestogen for Prevention of Preterm birth International Collaborative (EPPPIC) project aims to reduce uncertainty about the specific conditions in which progestogen may (or may not) be effective in preventing or delaying preterm birth and improving birth outcomes. Methods: The design of the study involves international collaborative individual participant data meta-analysis comprising systematic review, re-analysis, and synthesis of trial datasets. Inclusion criteria are as follows: randomized controlled trials comparing progestogen versus placebo or nonintervention, or comparing different types of progestogen, in asymptomatic women at risk of preterm birth. Main outcomes are as follows; fetal/infant death, preterm birth or fetal death (<=37 weeks, <=34 weeks, <= 28 weeks), serious neonatal complications or fetal/infant death, neurosensory disability (measured at 18 months or later) or infant/child death, important maternal morbidity, or maternal death. In statistical methods, IPD will be synthesized across trials using meta-analysis. Both ‘two-stage’ models (where effect estimates are calculated for each trial and subsequently pooled in a meta-analysis) and ‘one-stage’ models (where all IPD from all trials are analyzed in one step, while accounting for the clustering of participants within trials) will be used. If sufficient suitable data are available, a network meta-analysis will compare all types of progesterone and routes of administration extending the one-stage models to include multiple treatment arms. Discussion: EPPPIC is an international collaborative project being conducted by the forming EPPPIC group, which includes trial investigators, an international secretariat, and the research project team. Results, which are intended to contribute to improvements in maternal and child health, are expected to be publicly available in mid 2018. Description: EPPPIC group 2017-01-01T00:00:00Z http://repository.usmf.md:80/handle/20.500.12710/17674 Title: Patologia chirurgicală în sarcină: aspecte de conduită. Reviul literaturii Authors: Mihalcean, Luminiţa; Caproş, Hristiana; Bologan, Ion; Minciună, Nicoleta; Ţaulean, Cristina Abstract: About 2% of pregnant women require surgery during pregnancy for a non-obstetric indication. If the indication for a surgical procedure are present, then one can operate during each trimester without increasing the risk for the mother or the fetus. Surgery during pregnancy should ideally be performed in centers that have interdisciplinary experience in the surgical management of pregnant patients and where even in non-obstetric procedures, an obstetrician and a neonatologist are readily available.; Приблизительно у 2% беременных возможны хирургические вмешательства из-за не-акушерской патологии. Если есть показания на хирургическую процедуру, она может быть произведена в любом триместре беременности без повышенного риска для матери или плода. Хирургические вмешательства во время беременности должны быть сделаны в междисциплинарных центрах с опытом хирургического лечения беременных и где акушер и неонатолог доступны во время неакушерских процедур. Description: Universitatea de Stat de Medicină şi Farmacie ”Nicolae Testemiţanu” 2017-01-01T00:00:00Z