http://repository.usmf.md:80/handle/20.500.12710/359 2026-07-01T06:54:04Z http://repository.usmf.md:80/handle/20.500.12710/4690 Title: Variations of the mandibular canal, mandibular and mental orifices Authors: Pirov, Simcha; Pirov, Aviva Abstract: The present study assesses variabilities of mandibular canal, the relative position, size and shape of its mandibular and mental foramina, evaluates their measurement and relationship with various landmarks of the mandible in adults. The current study traced out that some of the mandibles had accessory mandibular and mental foramina. Variabilitatea canalului mandibular, orificiului mandibular şi mental Studiul de faţă elucidează variabilitatea canalului mandibular, poziţia relativă a orificiilor lui mandibular şi mental, evaluează datele de morfometria a acestora şi demonstrează raporturile lor cu diverse puncte de reper ale mandibulei la adulţi. În acest studiu au fost constatată prezenţa orificiilor supranumerare. Description: (Scientific Advisor - Assoc. Professor T. Hacina) Department of Human Anatomy 2012-01-01T00:00:00Z http://repository.usmf.md:80/handle/20.500.12710/4692 Title: Morphological variabilities of the skull Authors: Pirov, Aviva; Pirov, Simcha Abstract: The article describes different aspects of variability of the human skull: gender, age and ethnic. An attempt of systematization of the structural features of the skulls is undertaken În articol se descriu diferite aspecte referitoare la variabilitatea craniului uman: de sex, de vârstă şi apartenenţa etnică. Este întreprinsă încercarea sistimatizării particularităţilor structurale ale craniilor. Description: (Scientific Advisor - Assoc. Professor T. Hacina) Department of Human Anatomy 2012-01-01T00:00:00Z http://repository.usmf.md:80/handle/20.500.12710/4691 Title: Variability of the left atrioventricular and semilunar valves Authors: Harmelin, Roman; Zilbert, Anton Abstract: The study was performed in order to determine possible variations of the mitral and aortic semilunar valves and their frequency. Rezultatele cercetării demonstrează variante posibile ale valvei mitrale şi celei semilunare aortice şi frecvenţa lor. Description: (Scientific advisor - Assoc. Professor T. Hacina) Department of Human Anatomy 2012-01-01T00:00:00Z http://repository.usmf.md:80/handle/20.500.12710/4696 Title: Proliferarea limfovasculară în neoplazia scuamocelulară de cervix uterin Authors: Mazuru, Vitalie; Fulga, Veaceslav; Mazuru, Oxana; Globa, Tatiana; Şaptefraţi, Lilian Abstract: The aim of this research was the study of proliferative lymphatics microvascular density in preneoplastic and neoplastic lesions of uterine cervix. Material: squamous metaplasia – (n=22) cases, CIN I – (n=16), CIN II – (n=14), CIN III – (n=6), microinvasive carcinoma – (n=15), invasive carcinoma – (n=32). Methods: for histopathologic diagnosis and lesion’s stadialisation hematoxilin&eosin staining has been used. For identification of general LMVD and density of proliferative lymphatics the LSAB+/HRP Double Stain technique were performed. Two monoclonal antibodies have been used: anti D2-40 and anti Ki-67. Weidner hot spot modified method was used for lymphatic vessels quantification. Results: proliferative lymphatic vessels density in squamous metaplasia was equal with 0,93; CIN I – 1,4; CIN II – 3,33; CIN III – 4,56; microinvasive carcinoma – 3,01; invasive carcinoma – 2,14. Intratumoral lymphatics were small, flattened, without lumen. Peritumoral lymphatics were large, with distinct lumen. In peritumoral area were found 21 lymphatic vessels with tumor emboli inside, 8 of them were proliferative lymphatics. Conclusions: preneoplastic and neoplastic lesions of uterine cervix determine active formation of new lymphatic vessels. Lymphangiogenic switch begins in CIN I stage. In CIN III stage the LMVD is the highest. The intensity of tumor lymphangiogenesis is not smaller than in CIN stages. The spreading of tumor cells occurs through both types of lymphatic vessels: preexisting and newly formed. 38 Scopul lucrării a fost studierea densităţii microvasculare limfatice proliferante în leziunile preneoplazice şi neoplazice de cervix uterin. Material: metaplazie scuamoasă – (n=22) cazuri, CIN I – (n=14), CIN II – (n=12), CIN III – (n=6), carcinom microinvaziv – (n=15), carcinom invaziv – (n=32). Metode: hematoxilină şi eozină pentru diagnosticul histopatologic şi stadializarea leziunilor; dublă imunocolorare utilizând tehnica LSAB+/HRP Double Stain. Au fost utilizaţi pentru cercetare anti D2-40 şi anti Ki-67. Numărarea vaselor limfatice s-a făcumatut prin metoda hot spot modificat a lui Weidner. Rezultate: densitatea vaselor limfatice proliferante în metaplazia scuamoasă este egală cu 0,93; CIN I – 1,4; CIN II – 3,33; CIN III – 4,56; carcinom microinvaziv – 3,01; carcinom invaziv – 2,14. Limfaticele intratumorale au fost mici, colabate, iar cele peritumorale – medii sau mari, cu lumen evident. Au fost depistate 8 vase limfatice proliferante cu emboli tumorali în lumen. Concluzii: leziunile preneoplazice şi neoplazice determină activ formarea limfaticelor de neoformaţie, switch-ul limfangiogen începe în CIN I şi atinge apogeul în CIN III. Intensitatea limfangiogenezei tumorale în carcinoamele invazive nu este mai mică decât în CIN. Metastazarea celulelor neoplazice are loc atât prin limfaticele preexistente, cât şi prin cele de neoformaţie. Description: Catedra Histologie, Citologie şi Embriologie 2012-01-01T00:00:00Z