http://repository.usmf.md:80/handle/20.500.12710/914 2026-04-07T09:15:49Z http://repository.usmf.md:80/handle/20.500.12710/30380 Title: Social and demographic factors in post-stroke patients with chronic musculoskeletal pain Authors: Melnic, Adrian; Pascal, Oleg; Pleșca, Svetlana; Bilan, Anastasia; Bulai, Marina Abstract: Introduction. Post-stroke patients often suffer from chronic musculoskeletal pain, which can significantly impact their quality of life. Understanding the social and demographic factors that influence chronic musculoskeletal pain in these patients can help enhance effective interventions. This study aimed to investigate the demographic factors associated with chronic musculoskeletal pain in post-stroke patients. Methods. This retrospective study was conducted on 270 poststroke patients. Demographic factors analyzed were age decade, age category, gender, residency, and VAS pain score. The VAS pain score was used to measure pain intensity. Results. Out of 270 patients, 56 reported chronic musculoskeletal pain. The most prevalent age group was patients between 60-69 years (42.9%). Patients over the age of 65 reported chronic musculoskeletal pain more frequently than those between the ages of 40-65. Male patients reported having pain more frequently than female patients (67.9% vs. 32.1%). Rural inhabitants had a higher prevalence of chronic musculoskeletal pain (53.6%) compared to urban inhabitants. Men reported higher pain intensity than women, with a mean VAS score of 5.05 and 4.06, respectively. Conclusion. Older age, male gender, rural residency, and higher pain intensity were associated with a higher prevalence of chronic musculoskeletal pain. Healthcare professionals should develop tailored interventions for post-stroke patients with chronic musculoskeletal pain. However, further research is needed to investigate the social factors associated with chronic musculoskeletal pain in this patient population. 2023-01-01T00:00:00Z http://repository.usmf.md:80/handle/20.500.12710/30379 Title: Multimorbidity as a predictor of functional outcomes for stroke rehabilitation Authors: Melnic, Adrian; Pascal, Oleg; Chihai, Victoria; Cîrîm, Mihail Abstract: Introduction: Multimorbidity, characterized by the coexistence of multiple chronic conditions, presents a significant challenge in the rehabilitation of stroke survivors. Understanding the impact of multimorbidity on functional outcomes is crucial for optimizing post-stroke care. This study aimed to investigate the association between multimorbidity and functional outcomes in stroke survivors undergoing rehabilitation. Materials and Methods: Descriptive statistics were employed to analyze data from 270 stroke survivors. Multimorbidity was assessed based on the count of chronic conditions, and its influence on functional outcomes was evaluated using the Barthel Index scores. The reported statistics included means, 95% confidence intervals, and standard deviations. Results: Among the stroke survivors, 95.2% had multimorbidity, with 54.4% falling into the group with fewer than four chronic conditions and 49.6% in the group with four or more conditions. The mean Barthel Index score for stroke survivors with greater than four comorbidities was 60.74 (SD ± 13.08), with a 95% confidence interval ranging from 58.51 to 62.98. In comparison, stroke survivors with fewer than four comorbidities had a mean Barthel Index score of 71.06 (SD ± 9.47), with a 95% confidence interval ranging from 69.45 to 72.67. Conclusions: The high prevalence of multimorbidity among stroke survivors underscores its potential negative impact on post-stroke rehabilitation outcomes. The findings suggest that stroke survivors with a greater number of comorbidities tend to have lower functional scores, indicating poorer rehabilitation outcomes. 2023-01-01T00:00:00Z http://repository.usmf.md:80/handle/20.500.12710/30378 Title: Impact of mood and cognition disorders in post stroke rehabilitation Authors: Melnic, Adrian; Pascal, Oleg; Pleșca, Svetlana Abstract: Introduction. Cognitive and mood disorders after stroke are common comorbidities being associated with poor rehabilitation outcomes. At the same time, these conditions can overlap and cause low level of functioning in stroke patients. The purpose of the study was to evaluate the incidence and distinctive profile of cognitive and mood disorders and its impact on rehabilitation outcomes. Material and methods. Individuals (N=60) with stroke admitted in the department of Neurological Rehabilitation of the Institute of Neurology and Neurosurgery, Chisinau, Republic of Moldova were evaluated using Montreal Cognitive Assessment Scale (MoCA), The Hospital Anxiety and Depression Scale (HADS), and Barthel Index at admission and discharge. Results. Cognitive dysfunction in post stroke rehab have been registered in 87 % (mild -27%, moderate -38 %, severe forms – 22 % ) with average MoCA score of 17.18 points (SD± 7,4 ). The most affected area of cognitive function was visuospatial perception, memory and attention. Functional outcomes measured by difference of Barthel Index at admission and discharge are higher in persons with higher cognitive score (Pearson’s r =+0.65). Anxiety and depression were present in 30 % and 35 % of study group having a mean score of 9.6 for anxiety (SD± 5,6) and 8.9 for depression (SD± 3,56) . A negative correlation between depression score vs anxiety score and functional outcomes were registered with a stronger statistical significance for depression (Pearson’s r=-0.59 versus -0.31) Conclusions. Cognitive intervention for training of visual perception, attention and memory can improve functional outcomes for post stroke rehabilitation. Cognitive and mood disorder occur frequently as comorbidities in stroke and have to be considered by the multidisciplinary team. 2020-01-01T00:00:00Z http://repository.usmf.md:80/handle/20.500.12710/28166 Title: Eficacitatea terapiei cu ozon în medicină: monografie Authors: Bodrug, Nicolae; Barba, Doina; Istrati, Viorel; Botezatu, Adriana 2012-01-01T00:00:00Z