http://repository.usmf.md:80/handle/20.500.12710/17999 The 5th International Medical Congress for Students and Young Doctors, May 14-17, 2014 Sat, 11 Apr 2026 17:39:22 GMT 2026-04-11T17:39:22Z http://repository.usmf.md:80/handle/20.500.12710/20358 Title: MedEspera: The 5th International Medical Congress for Students and Young Doctors: abstract book, 2014 Wed, 01 Jan 2014 00:00:00 GMT http://repository.usmf.md:80/handle/20.500.12710/20358 2014-01-01T00:00:00Z http://repository.usmf.md:80/handle/20.500.12710/19537 Title: Coronary sinus reconstruction - 2 cases report Authors: Grădinariu, George; Enache, Mihail; Corciova, Flavia; Anghel, Diana; Prisacari, Victor Abstract: Introduction: Coronary sinus and ostium primum (unique atrium type) atrial septal defects (ASD) represent rare congenital malformations (less than 1% o f total ASDs) and are frequently associated with persistent left superior vena cava (LSVC). The shunt is caused in the first case by the incomplete development of the wall between the coronary sinus and the left atrium and in the second case, the coronary sinus drains into the single atrial cavity. Case description: Two patients (I. P., 15 years, B. G., 12 years) were operated in 2013 in our clinic. In the first case, although enlargement of the coronary sinus was not identified during echography, angio-CT showed fenestration of the coronary sinus wall and cardiac catheterization documented the bidirectional shunt as well as the persistent LSVC. Moreover, the ASD was associated with patent ductus arteriosis and cor triatriatum. In the second case the ostium primum ASD and the persistent LSVC as well as an anterior mitral valve cleft were diagnosed by echography and CT. Both patients underwent elective surgery. The coronaiy sinus was reconstructed in both cases using autologous pericardial patches. Moreover, in the first patient the ductus arteriosis was ligated and the intraatrial trabeculum was excised. In the second case the interatrial septum was reconstructed with autologous pericardium. Both cases had an unremarkable postoperatory recovery. Conclusions: Both cases showed that although the diagnosis for these malformations requires multiple investigations, a surgical correction with good long term results is feasible if the mechanism of the shunt is well documented. Description: University of Medicine and Pharmacy "Gr. T. Popa”, Iasi, Cardiovascular Disease Institute, Iasi (IBCV Iasi) Wed, 01 Jan 2014 00:00:00 GMT http://repository.usmf.md:80/handle/20.500.12710/19537 2014-01-01T00:00:00Z http://repository.usmf.md:80/handle/20.500.12710/19536 Title: Extragastric manifestations of Helicobacter Pylori infection in Romanian population Authors: Popovici, Mihaela; Alexescu, Teodora Abstract: Introduction: Helicobacter pylori (H. pylori) is one of the most frequent causes of gastrointestinal infections worldwide. It is known that the immunological response evoked by the bacterium is an important determinant of gastric mucosal damage. Epidemiological studies have investigated H. Pylori as a pathogenic determinant of some extragastric disorders due tolow-grade inflammatory state, molecular mimicry mechanisms, interference with the absorbance of nutrients and drugs possibly influencing the occurrence or the evolution of many diseases. The main burden of infection is in the developing countries possibly reflecting the presence of geographical variability in the prevalence of both H. pylori infection and the considered extradigestive disorders. Purpose and objectives: The aim of this study is to determine the prevalence of systemic hypertension (HTA), ischemic cardiomyopathy (IC), dyslipidemia, type 2 diabetes mellitus (T2DM) and chronic obstructive pulmonary disease (COPD) in a series of patients with Helicobacter Pylori infection and explore the possible etiopathogenetic link between them. Materials and method: A total of 100 participants were divided into two groups according to the presence (n=45) or absence (n=55) of Helicobacter Pylori infection. The detection of bacteria was assessed by upper endoscopic gastric biopsies. The presence of HTA, IC, dyslipidemia, T2DM and COPD were investigated in the medical history of both groups. Results: One hundred patients (47 men, 53 women), aged 30-85 years (the mean 58.1) were included; 55% of patients were positive for H. pylori infection. Twenty-two (51%) of patients with H. Pylori infection presented HTA, compared to 24 (42%) subjects of H. Pylori negative, without semnificative difference between the two groups. (p=0.65). The presence of IC was significantly higher (46%) in H. Pylori positive group than (25%) of the group without infection (p=0.003). Nineteen patients (34%) H. pylori positive had T2DM, while 10 patients (23%) were found in the H. Pylori negative group, the difference being statistically insignificant (p=0.58). The most frequent extragastric manifestation for patients infected with H. Pylori was dyslipidemia (29.7%). The patients with H. Pylori had significantly higher levels of dyslipidemia (62%) compared with the non-infected group (25%) (p=0.002). Sixteen (25%) cases of COPD were found in H. Pylori positive group and 10 (26%) in the H. Pylori negative group without reaching statistically significant levels (p=0.71). Conclusion: The association between H. pylori infection and ischemic cardiomyopathy and dyslipidemia was revealed in this study. Although some authors found convincing evidence of the involvement of Helicobacter pylori as one possible cause of systemic hypertension, type 2 diabetes mellitus and chronic obstructive pulmonary disease, our results have failed to confirm the existence of this etiological association. Hence, the precise processes remain unclear and require further studies. Description: "luliu Hatieganu” University of Medicine and Pharmacy, Otorhinolaryngology Department, Cluj-Napoca, Romania Wed, 01 Jan 2014 00:00:00 GMT http://repository.usmf.md:80/handle/20.500.12710/19536 2014-01-01T00:00:00Z http://repository.usmf.md:80/handle/20.500.12710/19535 Title: Clinical profile, common thrombophilia markers and risk factors in 47 young patients with ischemic stroke Authors: Popa, Grigore Abstract: Introduction: Stroke is one of the most common causes of death worldwide, along with cardiovascular pathology and oncology. Hereditary or acquired thrombophilia is often associated with arterial-venous thrombosis. Ischemic stroke caused by thrombophilia has an incidence of approximately 1-4% of total cerebral vascular accidents, with a higher incidence in the period from 45 years old, representing a deficiency of antithrombin, protein C, protein S, factor mutations V Laiding, and associated risk factors. Purpose and objectives: In the period 2008-2012, a retrospective study was conducted on 47 patients, who have been identified and treated at the county hospital "Nicolae Oblu" from Iasi, Romania. Arterial thrombosis may occur as a result o f hereditary or acquired thrombophilia associated with an increase o f fibrinogen and dyslipidemia levels, along withthe risk factors. Materials and methods: O f the study was to identify the prevalence o f thrombophilia associated to the risk factors, present in case o f 47 patients, who experienced at least one episode o f arterial thrombosis. Forty-seven patients from Iasi, older than 45 years, who had at least one episode of ischemic stroke, were studied for three markers of thrombophilia (protein C, protein S and antithrombin III), the plasma levels of fibrinogen and lipoproteins, and risk factors. There were used basic methods of coagulation and the Clauss method for fibrinogen determination. This study included patients who experienced at least one episode of arterial thrombosis until the age of 45 years. Two patients, who are 47 and 50 years old, were included in the study because of the fact that the first episode of ischemic stroke occurred when they were younger than 45 years. We have also taken into account the presence of risk factors, such as smoking, dyslipidemia, family history, etc. The study excluded the patients younger than 45 years, and also other causes of hypercoagulability such as hypertension, liver disease, nephritic syndrome, malignancy, polycythemia, thrombocytosis, contraceptive use, hormone replacement, etc. Results: There were 47 patients (M / F 18/29) with an average age of 35.6 years (ranging from 18 to 50 years). From a total of 47 patients, 35 had their first episode of stroke, and 12 experienced at least the second one. 21 of the patients showed no abnormalities of the anticoagulation factors, 5 patients had protein C deficiency, 8 of them had protein S deficiency, 5 of them had an antithrombin III deficiency, 11 patients showed increased levels of fibrinogen, and 8 patients had dyslipidemia. Concerning the risk factors, 18 patients were smokers and 6 patients had a family history of arterial thrombotic accidents. A combination of thrombophilia markers and risk factors was seen in case of 24 of the 47 patients. The prevalence of risk factors: smoking 40%, the increased levels of fibrinogen and lipoprotein, about 17%, and family history 12%. Only two patients have shown a deficiency of anticoagulation markers in case of an experienced episode of cerebral-arterial thrombosis. Conclusion: The routine testing of fibrinogen could have a positive influence on the early recognition of young patients, who experienced an episode of cerebral-arterial thrombosis, recognition for the deficit of anticoagulation factors, since the presence of thrombophilia markers alone can very rarely be a factor for an ischemic stroke. Description: University of Medicine and Pharmacy "Gr.T.Popa" Iasi Wed, 01 Jan 2014 00:00:00 GMT http://repository.usmf.md:80/handle/20.500.12710/19535 2014-01-01T00:00:00Z