DC Field | Value | Language |
dc.contributor.author | Sili, Anastasia | - |
dc.date.accessioned | 2020-10-12T08:54:23Z | - |
dc.date.available | 2020-10-12T08:54:23Z | - |
dc.date.issued | 2020 | - |
dc.identifier.citation | SILI, Anastasia. The antioxidant profile of Solidago species. In: MedEspera: the 8th Internat. Medical Congress for Students and Young Doctors: abstract book. Chișinău: S. n., 2020, p. 376-377. | en_US |
dc.identifier.uri | https://medespera.asr.md/wp-content/uploads/ABSTRACT-BOOK.pdf | - |
dc.identifier.uri | http://repository.usmf.md/handle/20.500.12710/12100 | - |
dc.description | Department of Pharmacognosy and
Pharmaceutical Botany, Nicolae Testemitanu State University of Medicine and Pharmacy,
Chisinau, Republic of Moldova, The 8th International Medical Congress for Students and Young Doctors, September 24-26, 2020 | en_US |
dc.description.abstract | Introduction. Antioxidants from natural sources are valuable bioactive compounds with welldemonstrated
health potential for use in several human disorders. Some species of genus
Solidago represent a rich source of natural compounds with multi-pharmacological properties,
including phenolic compounds which express antioxidant activity.
Aim of the study. This paper provides a review of current studies on antioxidant activity of
Solidago species. The main purpose of the research represents the evaluation of the correlation
between phytochemical characteristics and antioxidative properties of Solidago species, and
methods used for determination of their antioxidant activity.
Materials and methods. The bibliographic complex study was performed using the databases
of scientific references: PubMed, ResearchGate, GoogleScholar and ScienceDirect.
Results. In recent years, great interest has been focused on researching and using natural
antioxidants in medicine and pharmacy applications, due to their considerable biological value.Several in vitro and in vivo studies revealed that the presence of phenolic compounds in plant
extracts could be related with important biological properties, such as antioxidant,
immunomodulatory, antimicrobial and anticancer activities. One of the main groups of
biologically active compounds in Solidago species (goldenrods) is represented by phenolic
compounds. According to the bibliographic review, the profile of phenolic compounds in
Solidago species varies significantly in qualitative and quantitative composition and strongly
depend on the species, plant part, ontogenetic development, geographic regions and
environmental conditions. It was revealed the widely used methods for determination of
phytochemical and antioxidant profiles of goldenrods, such as HPLC post-column assays,
DPPH and ABTS radical scavenging activity assays, using the reference antioxidant Trolox. It
was evaluated the principal radical scavengers in chemical profile of goldenrods: phenolic
compounds of sp. S. canadensis and S. virgaurea differed with predominant antioxidant
activity of rutin, chlorogenic and 3,5-dicaffeoylquinic acids; of sp. S. gigantea − quercitrin,
chlorogenic and 3,5-dicaffeoylquinic acids; of sp. S. graminifolia − chlorogenic acid, quercitrin
and hyperoside. Consequently, these compounds can be considered as antioxidant activity
markers in phytochemical profiles of the corresponding Solidago species.
Conclusions. Several studies predict the importance of Solidago species as valuable raw
materials of biologically active phenolic compounds, which express important
pharmacological effects and possess antioxidant activity. | en_US |
dc.language.iso | en | en_US |
dc.publisher | MedEspera | en_US |
dc.subject | Solidago species | en_US |
dc.subject | antioxidant activity | en_US |
dc.subject | phenolic compounds | en_US |
dc.title | The antioxidant profile of Solidago species | en_US |
dc.type | Article | en_US |
Appears in Collections: | MedEspera 2020
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