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Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/12901
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dc.contributor.authorGaidarji, Olga
dc.contributor.authorRevenco, Ninel
dc.date.accessioned2020-11-11T14:55:43Z
dc.date.available2020-11-11T14:55:43Z
dc.date.issued2020-10
dc.identifier.urihttp://repository.usmf.md/handle/20.500.12710/12901
dc.identifier.urihttps://stiinta.usmf.md/ro/manifestari-stiintifice/zilele-universitatii
dc.descriptionNicolae Testimitanu State University of Medicine and Pharmacy of the Republic of Moldova, Congresul consacrat aniversării a 75-a de la fondarea Universității de Stat de Medicină și Farmacie „Nicolae Testemițanu” din Republica Moldova, Ziua internațională a științei pentru pace și dezvoltareen_US
dc.description.abstractIntroduction. Raynaud's Phenomenon (RP) is an episodic reaction to cold or stress, manifested as a change in extremity skin color. There are two types of RP. Primary RP is due to functional changes in the vessels, while secondary is due to endothelial injury in the context of connective tissue diseases (CTD). Purpose. To evaluate the role of capillaroscopy in the differentiation of primary and secondary pediatric RP. Material and methods. We conducted a search in PubMed database with the following search-terms: ”Raynaud phenomenon in children”, ”Pediatric Raynaud phenomenon”, ”Capillaroscopy in children”, ”Capillaroscopy in childhood”. A literature review was performed to analyze the existing data on RP in children. Results. RP is reported as a first symptom of rheumatic disease in 61- 70% of patients with systemic sclerosis, 58% of patients of patients with mixed connective tissue disease and 56% of patients with overlap syndrome. The differentiation of primary RP from secondary RP as well as detecting the markers that suggest its progression to CTD could facilitate early diagnosis of these diseases. Capillaroscopy is a simple, non-traumatic and cost-efficient tool with a major role in the differentiation of RP based on the capillaries look. Normal aspect suggests primary RP (fig.1), while altered shape and density – the presence of a CTD (fig.2, 3, 4). Conclusions. The application of capillaroscopy for differential diagnosis between primary and secondary Raynaud phenomenon in children for an early diagnosis of CTD could shed light on pathogenetic and evolutive aspects, but also on the treatment response.en_US
dc.language.isoenen_US
dc.publisherUniversitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu"en_US
dc.subjectcapillaroscopyen_US
dc.subjectchildrenen_US
dc.subjectendothelial injuryen_US
dc.titleThe role of capillaroscopy in the assessment of children with Raynaud phenomenonen_US
dc.typeOtheren_US
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