Prevalenţa sindromului cardiorenal 2/4 la pacienţii cu insuficienţă cardiacă cu fracţie de ejecţie redusă sau moderat redusă

Abstract

Prevalence of cardiorenal diseases is increasing and is accompanied by high mortality and morbidity. The aim of this study was to estimate the prevalence of type 2/4 cardiorenal syndrome in heart failure patients with reduced ejection fraction. The retrospective study included 194 heart failure patients with reduced and moderate-reduced ejection fraction hospitalized in January 2014 – December 2015 in the Department of Cardiology, CH “Sfanta Treime”. 194 patients were evaluated: 113 subjects with moderate-reduced ejection fraction (EF) 40-49%; and 81 subjects with reduced EF <40%. Patients with moderate-reduced EF were 67.89 y.o., 49.6% were men. The estimative glomerular filtration rate (GFRe) was 73.15 mL/min/1.73 m2, GFRe ≤ 60 mL/ min/1.73 m2 was recorded in 30.9%. The proteinuria prevalence was 62.8% and 78.57% in those with GFRe ≤ 60 mL/ min/1.73 m2 . Patients with reduced EF had mean age 64.69 years, 74.07% men. GFRe was 76.37 mL/min/1.73 m2 , GFRe ≤ 60 mL/min/1.73 m2 was recorded in 28.39% cases. The proteinuria prevalence was 77.8% in the sample, and 100% in those with GFRe ≤ 60 mL/min/1.73 m2. The results confirm that the prevalence of renal impairment in heart failure is high, whether we focus on GFR or proteinuria.