Platelet-rich plasma in treatment of degenerative and traumatic lesions

Abstract

Objectives: Platelet-rich plasma (PRP) is defined as a portion of the plasma fraction of autologous blood having a platelet concentration above baseline PRP also has been referred to as platelet-enriched plasma, platelet-rich concentrate, autologous platelet gel, and platelet releasate. PRP serves as a growth factor agonist and has both mitogenic and chemotactic properties. It contains a high level of platelets and a full complement of clotting and growth factors. Analyze of methods use PRPtherapy in different osteo-articular diseases and artroscopical surgery, benefits comparative with surgery without PRPtherapy, benefits PRP-therapy in postsurgical rehabilitation. Methods: The study includes analysis of cases of non-surgical and arthroscopic treatment of patients with traumatic injuries and degenerative medial femoral condyle chondropathy associated with grade 2-3 treatment that followed in 2013-2015. Clinical evaluation was performed by visual- verbal scale (VAS) in all patients, analysis of five significant factors for patients: pain, mobility, functional disability, return to work loaves disease, satisfaction followed effective treatment. Cartography was the best MRI investigation, which has proven effective for stimulating regenerative chondral. Results: the result was significantly better in patients with chondropathy that followed PRP therapy, clinical improvement is much taller than improving ascertained by MRI. The greatest differences in satisfaction or certificate received treatment and return to usual activities. For patients with synovitis brief duration of postsurgical patients that followed PRP postsurgery therapy was 3 times smaller. Conclusions: 1. The use of PRP therapy in patients with medial femoral condyle chondropathy gr.2-3 in postsurgical rehabilitation 2 times shortened recovery period. 2. The number of people who returned to work or professional sports was 35% higher in the group that followed PRP therapy 3. High efficiency PRP therapy allows to recommend the conduct regular medical rehabilitation in this patient group.