Particularităţile hemostazei la pacienţii cu ciroză hepatică decompensată în transplantul hepatic

Abstract

The role of the liver in the hemostasis system is very important because the synthesis of the clotting factors takes place here. Hemorrhage or hemorrhagic manifestations are some of the common clinical problems identified in patients with hepatic pathologies. Keeping the balance between procoagulant levels and anticoagulant proteins determines the risk of developing hemorrhage or thrombosis. The imbalance in hemostasis in patients with hepatic pathologies is hypercoagulable and predisposes to thrombotic complications. Risk factors for thromboembolic disease in patients with TH are: abnormal thrombin generation, platelets activation due to inflammation and venous stasis, thromboplastin release due to clamping / declination, reperfusion syndrome, catheter microtromps, intestinal ischemia, increased pulmonary arterial pressure, anatomical or technical cause.