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- IRMS - Nicolae Testemitanu SUMPh
- REVISTE MEDICALE NEINSTITUȚIONALE
- Sănătate Publică, Economie şi Management în Medicină
- Sănătate Publică, Economie şi Management în Medicină 2016
- Sănătate Publică, Economie şi Management în Medicină Nr. 2 (66) / 2016
Please use this identifier to cite or link to this item:
http://hdl.handle.net/20.500.12710/1517
Title: | Tratamentul contemporan fără interferon, cu inhibitori de proteaze Viekirax și Exviera în asociere cu Copegus la un pacient cu ciroză hepatică de etiologie virală C, Clasa Child-Pugh A |
Other Titles: | Contemporary treatment with interferon free regiment with protease inhibitors Viekirax in combination with Exviera and Copegus in cirrhotic patient С viral etiology, class А Child-Pugh Современное лечение с помощью ингибиторов протеазы Viekirax в сочетании с Exviera и Copegus без интерферона у больного с циррозом печени вирусной этиологии HCV, класс Child-Pugh A |
Authors: | Năstase, Viorica Matcovschi, Sergiu |
Keywords: | protease inhibitors;liver cirrhosis HCV etiology;sustained virologic response |
Issue Date: | 2016 |
Publisher: | Asociația Obștească ”Economie, Management și Psihologie în Medicină” din Republica Moldova |
Citation: | NĂSTASE, Viorica, MATCOVSCHI, Sergiu. Tratamentul contemporan fără interferon, cu inhibitori de proteaze Viekirax și Exviera în asociere cu Copegus la un pacient cu ciroză hepatică de etiologie virală C, Clasa Child-Pugh A. In: Sănătate Publică, Economie şi Management în Medicină. 2016, nr. 2(66), pp. 100-102. ISSN 1729-8687. |
Abstract: | For 12 weeks it was possible to obtain a 100% sustained virusological response for the patient with Child-Pugh A cirrhosis stage 6 points genotype 1b that administrated protease inhibitors: Exviera and Viekirax in associated with Ribavirin. From the side effects were fatigue and insomnia. Patients with HCV cirrhosis, stage Child-Pugh A and B have a shorter survival, and therefore should be treated with protease inhibitors preferentially to hepatitis HVC. After the disease is eliminated, the evolution speed of the disease is decreased, because the virus is no longer destroying the liver cells and decreases the risk of HCC, slow regression of fi brosis takes place, thus cirrhosis therefore is treated further. В течение 12 недель можно было получить 100% устойчивый вирусологический ответ у больных с циррозом печени вирусной этиологии VHC класс ChildPugh А, генотипа 1b, которые принимали ингибиторы протеаз Exviera и Viekirax в сочетании с рибавирином. Побочные эффекты были замечены: утомляемость и бессонница. Больные с циррозом печени HCV класса Child-Pugh А и В имеют меньше шансов на выживание, следовательно, должны получить лечение с ингибиторами протеазы предпочтительно по сравнению с больными с гепатитом HCV. После эрадикации вируса снижается скорость эволюции заболевания, так как вирус больше не разрушает клетки печени и снижает риск ГЦК и достигается медленная регрессия фиброза, поэтому нужно лечить дальше цирроз печени. |
URI: | http://repository.usmf.md/handle/20.500.12710/1517 http://revistaspemm.md/wp-content/uploads/2019/05/cm2_66_2016cg.pdf |
ISSN: | 1729-8687 |
Appears in Collections: | Sănătate Publică, Economie şi Management în Medicină Nr. 2 (66) / 2016
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