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Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/15265
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dc.contributor.authorPlacinta, Gheorghe
dc.contributor.authorVorojbit, Valentina
dc.contributor.authorPantea, Victor
dc.contributor.authorCojuhari, Lilia
dc.contributor.authorCebotarescu, Valentin
dc.contributor.authorPlacinta, Lidia
dc.contributor.authorCroitoru, Dan
dc.date.accessioned2021-01-19T16:18:26Z
dc.date.available2021-01-19T16:18:26Z
dc.date.issued2020
dc.identifier.citationPLACINTA, Gheorghe, VOROJBIT, Valentina, PANTEA, Victor. et al. Clostridium difficile infection in the intensive care unit. In: The Moldovan Medical Journal. 2020, vol. 63, no. 6, pp. 63-67. ISSN 2537-6381. DOI: 10.5281/zenodo.4028393
dc.identifier.issn2537-6381
dc.identifier.urihttps://doi.org/10.5281/zenodo.4028393
dc.identifier.urihttp://moldmedjournal.md/wp-content/uploads/2020/10/63-6-00-Spaltul-3-din-06-10-20-final.pdf
dc.identifier.urihttp://repository.usmf.md/handle/20.500.12710/15265
dc.description.abstractAbstract Background: Clostridium difficile (CD) infection is widespread throughout the world, showing an increased incidence over the recent years and may cause severe forms of disease. This infection most commonly affects patients whom were administered antibiotics. An increased resistance to commonly used antibiotics is associated with Clostridium difficile infection (CDI). CD has a generally recognized infectious potential on a clinical ground. CDI is unpleasant and may sometimes cause serious bowel disorders that are usually treated with another course of antibiotics. The evolution of CD infection depends on the individual characteristics of the patient along with risk factors, associated diseases as well as the particularities of the recommended treatment. However, even under the conditions of a correct and complete treatment the risk of the disease relapse is estimated to occur depending on risk factors. Many clinical instruments that are designated for the purposes to treat non-infectious diseases can be useful in estimating the severity of an infection. This review is important for understanding the abusive and irrational prescription of various groups of antibiotics, often unjustified, including the ones used in the treatment of an infection with SARS-CoV-2. Conclusions: These infections mostly occur in people aged 65 and older that receive medical care, including antibiotics administration, people with a long-term hospital stay, people with a weakened immune system or with a previous CD infection. The following measures, in order to reduce the risk of CDI in patients, should be considered: hand hygiene, avoidance of unnecessary administration of antibiotics – the antibiotic treatment is recommended only if it is prescribed by an experienced specialist, avoidance of unnecessary administration of drugs that reduce gastric acidity, because it favors the invasion of the gastrointestinal tract with CD.en_US
dc.language.isoenen_US
dc.publisherThe Scientific Medical Association of the Republic of Moldovaen_US
dc.relation.ispartofThe Moldovan Medical Journal: The 75th anniversary of Nicolae Testemitanu State University of Medicine and Pharmacy of the Republic of Moldova (1945-2020)en_US
dc.subjectclostridium difficileen_US
dc.subjectrisk factorsen_US
dc.subjecttreatment optionsen_US
dc.subject.ddcUDC: 616.98:579.852.13+616-083.98:614.2en_US
dc.titleClostridium difficile infection in the intensive care uniten_US
dc.typeArticleen_US
Appears in Collections:The Moldovan Medical Journal, Vol. 63, No 6, December 2020

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