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Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/16750
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dc.contributor.authorChornopyshchuk, Roman
dc.date.accessioned2021-05-08T15:21:57Z
dc.date.available2021-05-08T15:21:57Z
dc.date.issued2021
dc.identifier.citationCHORNOPYSHCHUK, Roman. Experimental substantiation of hyperthermic exogenous and endogenous factors prompt neutralization in burn injuries. In: The Moldovan Medical Journal. 2021, vol. 64, no 2, pp. 53-57. ISSN 2537-6381. DOI: https://doi.org/10.52418/moldovan-med-j.64-2.21.10
dc.identifier.issn2537-6381
dc.identifier.issn2537-6373
dc.identifier.urihttp://moldmedjournal.md/wp-content/uploads/2021/05/64-2-Spaltul-2-vers-3-din-05-05.pdf
dc.identifier.urihttps://doi.org/10.52418/moldovan-med-j.64-2.21.10
dc.identifier.urihttp://repository.usmf.md/handle/20.500.12710/16750
dc.descriptionDepartment of General Surgery, National Pirogov Memorial Medical University, Vinnytsya, Ukraineen_US
dc.description.abstractAbstract. Background: High mortality and disability of patients with critical and supercritical burns, long-term treatment, unsatisfactory aesthetic and functional results lead to the search for ways to provide assistance aimed at counteracting the formation of a mass of necrotic tissue, which is crucial for life or death of the victim. Material and methods: The experimental study was performed on 60 sexually mature Wistar rats, which were on a regular diet and weighed 150-160 g. The experimental animals were divided into the main and control groups and were used to simulate burns with boiling water of IIb degree. Results: The traumatic effect of hyperthermic exogenous and endogenous damage factors of the animals in the main group were immediately neutralized by a gauze napkin soaked in water at a temperature of 18-20 ° C immediately after the simulation of burns, the duration of which became the criterion for dividing them into subgroups. In animals of subgroup 1 the time of application of a wet wipe to the burn area was 1 min., in the 2nd subgroup it was 5 min., 3rd subgroup – 10 min., 4th subgroup – 15 min., 5th subgroup – 20 min. The application napkin was changed when it was heated to 34 °C. Such applications were not performed to the animals of the control group. Conclusions: The conclusion was made on the necessity of prompt neutralization of traumatic action of hyperthermic exogenous and endogenous damage factors as the main elements of burn wound depth. For a broader understanding of action mechanisms of the suggested technology of self-help and mutual first aid as well as the nature of the impact of neutralization directly on the tissues, it is advisable to supplement the research with morphological methods.en_US
dc.language.isoenen_US
dc.publisherThe Scientific Medical Association of the Republic of Moldovaen_US
dc.relation.ispartofThe Moldovan Medical Journalen_US
dc.subjecthyperthermic factorsen_US
dc.subjectburnsen_US
dc.subjectneutralizationen_US
dc.subjectfirst aiden_US
dc.subjectnecrotic tissuesen_US
dc.subject.ddcUDC: 616-001.17:614.88:612.8en_US
dc.titleExperimental substantiation of hyperthermic exogenous and endogenous factors prompt neutralization in burn injuriesen_US
dc.typeArticleen_US
Appears in Collections:The Moldovan Medical Journal, Vol. 64, No 2, June 2021

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