Eight channel audiosystem to control the course of neurophysiological experiment

Abstract

Introduction: Visualization of processes that are happening in an organism is implemented by means of rapid progress of electronics and computer systems. Especially valuable is visualization of physiological processes in central nervous system as they are short-term, unexplored, and complicated in their mechanism. We propose a new controlling system over the course of neurophysiological experiment during implantation into a brain of a rat multichannal electrode. Materials and Methods: Eight channel original steel microelectrode with interspaces between each conductor. Through the trepanation opening the electrode was placed stereotaxicaly in motor cortex under narcosis. A chain of devices pre-amplifier, filters, post-amplifier, conductor and receiver were produced in neurophysiological experiment lab of National Pirogov Memorial Medical University. Registration of biopotentials is held through analog-to-digital converter on magnetic carrier at the same time potential from each channel was passed to eight channel amplifier and then to dynamics placed along the perimeter of a lab. Discussion results: The same time with visual control over neurons’ biopotentials we controlled the course of experiment using audiosystem. Conclusion: The proposed device improves the perception of the experiment course by the researcher, helps to imagine the spatial arrangement of neurons surrounding the eight channel electrode and provides new opportunities for assessment of interaction between neurons.