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Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/18079
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dc.contributor.authorGavriluta, Diana
dc.contributor.authorGasnas, Alexandru
dc.contributor.authorGroppa, Stanislav
dc.date.accessioned2021-10-02T20:34:48Z
dc.date.available2021-10-02T20:34:48Z
dc.date.issued2021
dc.identifier.citationGAVRILUTA, Diana, GASNAS, Alexandru, GROPPA, Stanislav. Assessment of risk factors in post-stroke cognitive impairment. In: The Moldovan Medical Journal. 2021, vol. 64, no 3 (Neuro Congress Issue), p. 32. ISSN 2537-6381.
dc.identifier.issn2537-6381
dc.identifier.issn2537-6373
dc.identifier.urihttp://moldmedjournal.md/wp-content/uploads/2021/09/Congres-Neuro-2021-Spaltul-11.pdf
dc.identifier.urihttp://repository.usmf.md/handle/20.500.12710/18079
dc.description.abstractBackground: Cognitive impairment is a frequent symptom in post-stroke patients, with a prevalence range of 20% to 80%. Our study’s aim was to analyze the previously reported risk factors in order to highlight predictors of a poor prognosis in post-stroke cognitive impairment. Articles containing the key words: “cognitive impairment”, “stroke”, “risk factors” were selected from PubMed databases. The following filters were applied: article type – meta-analysis, review, systematic review; period of time – 5 years; language – English; species – humans; age – 45 – 65+ years. 46 results were identified, but only 20 articles were selected as relevant. Analyzing identified data, we found out that the following risk factors had a strong association with cognitive impairment after stroke – in 60 – 80% of cases: increased age, low educational status, vascular comorbidities, prior transient ischemic attack or recurrent stroke, depressive illness, cerebral atrophy, white matter lesions, alcohol use. Also, we identified other risk factors with a low association – in 20 – 30% of cases with cognitive impairment after stroke: family history, genetic variants, carotid plaques, smoking, paresis, elevated homocysteine, low-density lipoprotein, uric acid, low triiodothyronine syndrome, anemia, decreasing serum retinoic acid level, elevated serum rheumatoid factor and matrix metalloproteinases-9 levels. Conclusions: This literature review confirms the existence of studies with a high level of evidence on risk factors which trigger cognitive impairment in post-stroke patients. Acknowledgement of these risk factors could improve stroke management and rise these patients’ quality of life.en_US
dc.language.isoenen_US
dc.publisherThe Scientific Medical Association of the Republic of Moldovaen_US
dc.relation.ispartofThe Moldovan Medical Journalen_US
dc.subjectstrokeen_US
dc.subjectcognitive impairmenten_US
dc.subjectrisk factorsen_US
dc.titleAssessment of risk factors in post-stroke cognitive impairmenten_US
dc.typeOtheren_US
Appears in Collections:The Moldovan Medical Journal, Vol. 64, No 3, September 2021

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