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Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/18144
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dc.contributor.authorSoltan, Ilya-
dc.contributor.authorLukashou, Raman-
dc.date.accessioned2021-10-08T13:10:14Z-
dc.date.available2021-10-08T13:10:14Z-
dc.date.issued2021-
dc.identifier.citationSOLTAN, Ilya, LUKASHOU, Raman. The penetrating ability of Silybum marianum flavolignans in vitro. In: Revista Farmaceutică a Moldovei. 2021, vol. 45, nr. 1, pp. 67-71. ISSN 1812-5077.en_US
dc.identifier.issn1812-5077-
dc.identifier.urihttp://repository.usmf.md/handle/20.500.12710/18144-
dc.descriptionBelarusian State Medical University, Minsk, Republic of Belarusen_US
dc.description.abstractRezumat. În articol sunt prezintate rezultatele determinării capacităţii de penetrare a flavolignanilor din armurariu, utilizând modele in vitro. Cea mai bună capacitate de penetrare a flavolignanilor este asigurată de combinaţia extractului uscat de armurariu cu suma saponinelor totale de lemn dulce (89,57% masă), standardului de silimarină cu aceleași saponine (85,75% masă), extractului uscat de armurariu cu lecitină de soia (84, 37% masă). La utilizarea dodecilsulfatului de sodiu (SDS), are loc o diferenţiere clară a curbelor de absorbţie, fapt ce permite utilizarea SDS ca model pentru studierea absorbţiei flavolignanilor.en_US
dc.description.abstractAbstract. The article presents the results of determining the penetrating ability of milk thistle flavolignans using in vitro models. The best penetrating abilityof flavolignans is provided by a combination of milk thistle dry extract with the total licorice saponins (89.57% by weight), standard of sylimarinewith saponins (85.75% by weight), dry extract with soy lecithin (84, 37% by weight). With the use of sodium dodecyl sulfate (SDS), a clear differentiation of the absorption curves occurs, which may allow the use of SDS as a model for studying the absorption of flavolignans.en_US
dc.language.isoenen_US
dc.publisherAsociația Farmaciștilor din Republica Moldovaen_US
dc.relation.ispartofRevista Farmaceutică a Moldoveien_US
dc.subjectMilk thistleen_US
dc.subjectpenetrating abilityen_US
dc.subjectflavolignansen_US
dc.subject.ddcCZU: 582.998.1:547.9en_US
dc.titleThe penetrating ability of Silybum marianum flavolignans in vitroen_US
dc.title.alternativeCapacitatea penetrantă a flavolignanilor din Silybum marianum in vitroen_US
dc.typeArticleen_US
Appears in Collections:Revista Farmaceutică a Moldovei Nr. 1 Vol. 45, 2021

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