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Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/1846
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dc.contributor.authorCotelea, Tamara
dc.contributor.authorLungu, Tatiana
dc.contributor.authorStati, Lilia
dc.contributor.authorArama, Efim
dc.date.accessioned2019-06-22T13:04:27Z-
dc.date.available2019-06-22T13:04:27Z-
dc.date.issued2011
dc.identifier.citationCOTELEA, Tamara, LUNGU, Tatiana STATI, Lilia, ARAMA, Efim. Analiza chimico-toxicologică a amitriptilinei. In: Anale ştiinţifice ale USMF “Nicolae Testemiţanu”. Ed. a 12-a. Chişinau: СEP Medicina, 2011, vol. 1: Probleme medico-biologice şi farmaceutice, pp.406-409.en_US
dc.identifier.urihttp://repository.usmf.md/handle/20.500.12710/1846-
dc.descriptionCatedra Chimie farmaceutică şi toxicologică USMF „N.Testemiţanu” Catedra Biofizică, Informatică şi Fiziologia omului „N.Testemiţanu”en_US
dc.description.abstractThere was elaborated optimum isolation and extraction conditions of amitriptiline from biological fluids. We used physico – chemical methods to identify amitriptiline: chromatography on a thin layer by utilizing four systems of solvents, spectrophotometrical method in UV, HPLC.The methods processed by us for in biological tests “in vitro” are specific and reproductive, and they are recommended for the study of amitriptiline in biological fluids. Au fost determinate condiţiile optime de izolare şi extragere a amitriptilinei din lichidele biologice Am aplicat metodele fizico-chimice de identificare a amitriptilinei: cromatografia pe strat subţire utilizând patru sisteme de solvenţi, metoda spectrofotometrică în UV, HPLC. Metodele prelucrate de noi pentru amitriptilină în probele biologice „in vitro” sunt specifice şi reproductive şi ele se recomandă pentru studierea amitriptilinei în lichidele biologice.en_US
dc.language.isootheren_US
dc.publisherCEP Medicinaen_US
dc.subject.meshAmitriptylineen_US
dc.subject.meshAmitriptyline - toxicityen_US
dc.subject.meshAmitriptyline - blooden_US
dc.subject.meshAmitriptyline - isolation and purificationen_US
dc.subject.meshChromatography, Thin Layer - methodsen_US
dc.titleAnaliza chimico-toxicologică a amitriptilineien_US
dc.title.alternativeChemico-toxicological analysis of amitriptilineen_US
dc.typeArticleen_US
Appears in Collections:Chimie generală și farmaceutică. Tehnologia medicamentelor

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