| DC Field | Value | Language |
|---|
| dc.contributor.author | Gladâş, Valentina | |
| dc.contributor.author | Corcimaru, Ion | |
| dc.contributor.author | Robu, Maria | |
| dc.contributor.author | Chelea, Iurii | |
| dc.contributor.author | Musteaţă, Vasile | |
| dc.contributor.author | Mocanu, Irina | |
| dc.date.accessioned | 2019-06-22T13:13:33Z | - |
| dc.date.available | 2019-06-22T13:13:33Z | - |
| dc.date.issued | 2011 | |
| dc.identifier.citation | GLADAS, Valentina, CORCIMARU, Ion et al. Recidivele leucemiei acute promielocitare. In: Anale ştiinţifice ale USMF “Nicolae Testemiţanu”. Ed. a 12-a. Chişinau: СEP Medicina, 2011, vol. 3: Probleme actuale în medicina internă, pp. 347-351. | en_US |
| dc.identifier.uri | http://repository.usmf.md/handle/20.500.12710/1870 | - |
| dc.description | Catedra Hematologie şi Oncologie a USMF “N.Testemiţanu”
Instituţie Medico-Sanitară Publică Institutul de Oncologie din Moldova | en_US |
| dc.description.abstract | We have followed up 67 patients with acute promyelocytic leukemia, who underwent
combined treatment with ATRA and polychemotherapy (PCT). Complete remissions were
achieved in 55 (82,1%) cases. Early relapses were registered in 9 (34,6%) patients. Late relapses
developed in 17 ( 66.4%) cases, four of these patients abolished the treatment. Relapses more
often (82,4%) develop in the patients in first 3 years of complete remision, but in following
years the frecvency of relapses is significantly reduced.Repeated combined treatment with
ATRA and PCT appeared to be efficient in 5 (23,8%) cases.
Key words: Acute promyelocytic leukemia, All-trans-retinoic acid, relapse.
Sub supraveghere s-au aflat 67 de bolnavi de leucemie acută promielocitară, care au
primit tratament cu ATRA în combinaţie cu polichimioterapie. Remisiuni complete au fost
obţinute la 55 (82,1%) bolnavi. Recidive precoce au fost constatate la 9 (34,6%) pacienţi,
recidive tardive în 17 (66,4%) cazuri. Recidivele mai frecvent (82,4%) au aparut în primii 3 ani
de remisiune completă, ulterior cu scăderea lor considerabilă. Remisiune completă în
tratamentul recidivelor a fost obţinută la 5 (23,8%) bolnavi. | en_US |
| dc.language.iso | ro | en_US |
| dc.publisher | CEP Medicina | en_US |
| dc.subject.mesh | Acute Promyelocytic Leukaemia | en_US |
| dc.subject.mesh | Tretinoin | en_US |
| dc.subject.mesh | Recurrence | en_US |
| dc.title | Recidivele leucemiei acute promielocitare | en_US |
| dc.title.alternative | Relapses of acute promyelocitic leukemia | en_US |
| dc.type | Article | en_US |
| Appears in Collections: | Hematologie
|
