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Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/19465
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dc.contributor.authorLupascu, Aliona-
dc.date.accessioned2021-12-20T10:18:27Z-
dc.date.available2021-12-20T10:18:27Z-
dc.date.issued2014-
dc.identifier.citationLUPASCU, Aliona. The level of sexual hormones in women of reproductive age with cirrotic portal hipertension. In: MedEspera: the 5th Internat. Medical Congress for Students and Young Doctors: abstract book. Chișinău: S. n., 2014, p. 46.en_US
dc.identifier.urihttp://repository.usmf.md/handle/20.500.12710/19465-
dc.descriptionThe Institute of Mother and Child Care, Chisinau, Republic of Moldovaen_US
dc.description.abstractBackground: Chronic liver diseases are commonly associated, in dependence of severity and duration of disease, with menstrual cycle disorders such as amenorrhea and anovulation. In most of cases the possibility of pregnancy is poor but sometimes these women become pregnant. The aim: To estimate the concentration of sexual hormones in women of reproductive age with cirrhotic portal hypertension, in dependence of functional liver reserve Child Pugh. Materials and methods: We selected 60 women of reproductive age with cirrhotic portal hypertension, caused by chronic virus hepatitis. The functional liver reserve was determined, according to the Child A/B/C -36/10/4. We tested the plasmatic levels of estrogen, progesterone, LH and FSH. Results: In the first group in 36 cases (60%), where the functional reserve of liver Child Pugh A, was good, the medium level of E2 in all the phases of menstrual cycle was at upper admissible range (130,7±30,5pg/ml). In the second and the third group with poor functional reserve Child B,C in 24 cases (40%) the level of estrogen have been increased in all the phases of menstrual cycle (366,6±46,3pg/ml). This fact can be explicated by functional insufficiency of the liver and perturbances of protein synthesis in liver, which cause severe pathogenetic infringements in estrogenic metabolism. The plasmatic medium concentration of progesterone in the first group was 34,5±3,6 n mol/1 and in group with poor liver reserve it was a breakdown of progesterone contents till 16,7±3,4nmol/l (p<0,05).There were no significant statistic difference between the levels of LH and FSH in presented groups (p>0,05). Conclusions: The increased value levels of estrogen and poor concentration of progesterone in women with cirrhotic portal hypertension, explain the absence of menstruation and anovulatory cycles in patients with poor liver reserve, which are the main factors of infertility in these patients.en_US
dc.language.isoenen_US
dc.publisherMinistry of Health of the Republic of Moldova, State Medical and Pharmaceutical University Nicolae Testemitanu, Medical Students and Residents Associationen_US
dc.relation.ispartofMedEspera: The 5th International Medical Congress for Students and Young Doctors, May 14-17, 2014, Chisinau, Republic of Moldovaen_US
dc.subjectinfertilityen_US
dc.subjectsexual hormonesen_US
dc.subjectportal hypertensionen_US
dc.titleThe level of sexual hormones in women of reproductive age with cirrotic portal hipertensionen_US
dc.typeOtheren_US
Appears in Collections:MedEspera 2014



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