Microbiological and epidemiological features of microbial associations in septic infections in surgical departments

Abstract

Introduction: The problem of septic infections (SI) is still an actuality, despite the positive developments in the fight against infectious diseases Objective: The study of the microbiological and epidemiological characteristics of poly etiology of purulent-septic infections in surgical patient's general hospital Materials and methods: Isolation and identification of microorganisms was carried out by conventional methods. To identify clinical and epidemiological features performed a retrospective analysis of incidence, according to official registration in the recording and reporting hospital. Results: 108 strains of microorganisms were aallocated, belonging to the 11 species. Among Assiociants dominated by Staphylococcus aureus (35,18%), Acinetobacter baumannii and Staphylococcus epidermidis. Acinetobacter baumannii and Staphylococcus epidermidis predominated, and among Assiociants among monocultures. Enterobacter agglomerans, Proteus mirabilis recorded only in the association. For surgical patients the most frequent combination of established S.aureus, Staphylococcus epidermidis among themselves, as well as E.coli, Proteus spp., Entero-coccus spp. Most species of microorganisms occurred mainly in the form of associations. In general surgery the figure was equal to 64.3%, dominated by two-component association. The number of multidrug-resistant crops amounted to 25,1% (Acinetobacter baumannii, Staphylococcus aureus, Enterobacter agglomerans). Jaccard coefficient was highest for Staphylococcus aureus Staphylococcus epidermidis (68,9%) and Staphylococcus aureus c Acinetobacter baumannii (47,5%), which corresponds to the synergistic relationship. And in the associations and Staphylococcus epidermidis Acinetobacter koeffitsient 17.1 - has an antagonist relationship. The neutral attitude prevailed over the synergistic and antagonistic. The average incidence of polyetiology infections was 17 per 100. As a result of the study, the following clinical and epidemiological features of polyetiology of infections in surgical patients and risk factors for their development: the leading pathology in polyetiology infections - skin and subcutaneous tissue (70%). The age structure of patients was predominantly older age group (42 to 60), and the average age of the patients was 54. The main type of surgery - opening abscesses, phlegmon, limbs amputation. Poly etiology of infections in patients had more surgical interventions (70.1%) and it was found that more patients with infections were poly etiology necrectomy. Duration of hospital stay was 13.4 days on average. The intensity of the ABT was primarily a course. Conclusions: Organization of the microbiological monitoring of poly-etiology SI, is a necessary part of the surveillance of hospital infections.