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Please use this identifier to cite or link to this item: http://hdl.handle.net/20.500.12710/20186
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dc.contributor.authorDondas, Andrei-
dc.date.accessioned2022-02-17T11:52:46Z-
dc.date.available2022-02-17T11:52:46Z-
dc.date.issued2010-
dc.identifier.citationDONDAS, Andrei. Late complications following permanent pacemaker implantation. In: MedEspera: the 3rd Internat. Medical Congress for Students and Young Doctors: abstract book. Chișinău: S. n., 2010, p. 34.en_US
dc.identifier.urihttp://repository.usmf.md/handle/20.500.12710/20186-
dc.description.abstractThe objective of the work was to determine prospectively the rate of late complications (6, 12 months) following first implantation of a permanent pacemaker or generator replacement. To illustrate our pathology using 3 case reports with particular problems concerning the diagnosis and treatment options. We studied 126 consecutive patients with definite indications for permanent pacemaker implantation, included between 2006 and 2009. Generator replacement was required in 12 patients because of pulse generator electrical failure. In all cases a W I pacemaker was used. Implantation of the lead-catheter used right/left subclavian vein (108 cases vs. 18 cases) access. We realized a clinical follow-up (local pocket integrity, signs/symptoms for ipsilateral superior limb deep venous thrombosis or pulmonary thromboembolism-TEP) combined with biologic (D-dimers, fibrinogen, platelets), microbiologic (wound secretion, hemocultures) and imaging methods. Imaging follow-up protocol used venous ultrasound, ipsilateral superior limb phlebography, perfusion lung scintigram, transtoracic and transesophageal echocardiography. The overall rate of late complications was 23.8% in our study. There were infectious, thromboembolic complications and pacemaker syndrome signs/symptoms. Local pocket-related infection (pocket erosion/necrosis) with Staphylococcus aureus/epidermidis wad found in 7.14% of cases; in two cases Enterobacter/ Staphylococcus aureus septicemia complicated local infection. Infective endocarditis complicated evolution in one case (vegetation on the stimulation catheter). Late infectious complications rate was significantly lower after first implantation of the permanent pacemaker comparing generator replacement (1.4% vs. 6.5%) and also in the subgroup with prophylactic antibiotherapy (0.6% vs. 3.1%). Pacing electrode thrombosis was defined by ultrasound in 10 patients (12.6%) and by phlebography in 19.04%; echocardiography detected one case of thrombosis in right atrium and manifest TEP complicated evolution. In 2 cases there were clinical signs for superior limb deep venous thrombosis. Perfusion lung scintigram revealed high /intermediate probability for TEP in 5 patients, respectively 2 patients. In 3.17% of cases both types of complications were present. Pacemaker syndrome was manifest through mild symptoms/signs in 2 cases. Our data are comparable with literature concerning the rate of late infectious and thromboembolic complications. Pacing electrode thrombosis is frequently asymptomatic and underestimated in clinical terms. For this reason, the decision for anticoagulation is better individualized. Even conducted in rigorous asepsis conditions invasive technique is better followed by antibiotheraphy. The low incidence of pacemaker syndrome is in relation with follow-up period.en_US
dc.language.isoenen_US
dc.publisherNicolae Testemitanu State Medical and Pharmaceutical Universityen_US
dc.relation.ispartofMedEspera: The 3rd International Medical Congress for Students and Young Doctors, May 19-21, 2010, Chisinau, Republic of Moldovaen_US
dc.titleLate complications following permanent pacemaker implantationen_US
dc.typeOtheren_US
Appears in Collections:MedEspera 2010

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