DC Field | Value | Language |
dc.contributor.author | Mazur, Ecaterina | - |
dc.contributor.author | Valica, Vladimir | - |
dc.contributor.author | Uncu, Livia | - |
dc.date.accessioned | 2022-11-13T11:06:06Z | - |
dc.date.available | 2022-11-13T11:06:06Z | - |
dc.date.issued | 2022 | - |
dc.identifier.citation | MAZUR, Ecaterina, VALICA, Vladimir, UNCU Livia. The role of potassium in glucose intolerance: [poster]. In: Conferinţa ştiinţifică anuală "Cercetarea în biomedicină și sănătate: calitate, excelență și performanță", 19-21 octombrie 2022: culegere de postere electronice. 2022, p. 213. | en_US |
dc.identifier.uri | https://conferinta.usmf.md/wp-content/uploads/culegere_de_postere_2022.pdf | - |
dc.identifier.uri | http://repository.usmf.md/handle/20.500.12710/22454 | - |
dc.description.abstract | Introduction. Glucose intolerance can often be caused by severe hypokalemia due to a deficit in potassium balance (the normal serum potassium level in adults is 3.5-5.0 meq/L). Hypopotassemia is associated with impaired insulin secretion and decreased peripheral glucose utilization.
Purpose. The aim of the study is to analyze the role of potassium in formation of glucose intolerance that can result in increased risk for developing type 2 diabetes mellitus (T2DM).
Material and methods. Advanced bibliographic study of 41 bibliographic sources from databases: Medline, Scopus, HINARI, PubMed, Cochrane
Electronic.
Results.
The analysis of the evaluated bibliographic sources showed the closed relationship between potassium deficit and glucose intolerance. It may occur in aldosteronism or prolonged treatment with diuretics. The mechanism of potassium to control of blood glucose is at a cellular level where potassium-induced cell depolarization results in insulin secretion from pancreatic -cells.
According to the prospective cohort, it was found that high
potassium intake may be associated with a decreased risk for
T2DM. In addition, when patients with thiazide-induced
hypopotassemia took potassium supplements, the defects in insulin
release in response to glucose loads were corrected.
Conclusions. Hypopotassemia is associated with impaired insulin secretion and decreased peripheral glucose utilization, leading to carbohydrate intolerance and hyperglycemia. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Universitatea de Stat de Medicină şi Farmacie "Nicolae Testemiţanu" din Republica Moldova | en_US |
dc.relation.ispartof | Conferinţa ştiinţifică anuală "Cercetarea în biomedicină și sănătate: calitate, excelență și performanță", 2022 | en_US |
dc.subject | potassium | en_US |
dc.subject | glucose intolerance | en_US |
dc.subject | insulin | en_US |
dc.subject | diabetes | en_US |
dc.title | The role of potassium in glucose intolerance | en_US |
dc.type | Other | en_US |
Appears in Collections: | Conferinţa ştiinţifică anuală "Cercetarea în biomedicină și sănătate: calitate, excelență și performanță", 19-21 octombrie, 2022: Culegere de postere
|