Manifestation of diabetic autonomic genitourinary neuropathy

Abstract

Background. The prevalence of autonomic diabetic neuropathy is rising in patients globally. Diabetes mellitus (DM) increased risk of erectile deficiency (ED), of developing urinary incontinence, of urinary tract infection (UTI). Objective of the study. The aim is to show distinct variations in how autonomic genitourinary neuropathy (DUN) can manifest in individuals of different sexes. Material and methods. Analysis of literature (PubMed, google scholar Medline, Web of Science; Research conducted in the past 15 years). Results. 43% of women aged 50-64 and 51% of women aged 65-80 suffer from urinary incontinence caused by DUN. 15% of women with DM type 2 have experienced at least one UTI per annum. Approximately 13% of men with DM had increased severity of lower urinary tract infection LUTI). 52.2% of diabetic men experienced ED. Out of these men, 3 7.7% of DM type 1 men had ED and 57.7% of DM type 2 men had ED. Men had a 25-50% higher chance of having benign prostatic hyperplasia (BPH). Conclusion. Women with DUN have higher odds of female sexual dysfunction and UTI; more likely to experience urinary incontinence, increased urinary frequency, and challenges with voiding compared to men. Men with DUN have higher odds of LUTI, ED and orgasmic dysfunction; more likely to experience sexual dysfunction compared to women. Women also tend to have a worse prognosis because urinary neuropathy has a higher chance of developing complications compared to sexual dysfunctions.